English Journal

[Acute myeloid leukemia with monosomy 7 and inv(3)(q21q26.2) complicated with central diabetes insipidus].

Nanno S1, Hagihara K, Sakabe M, Okamura H, Inaba A, Nagata Y, Nishimoto M, Koh H, Nakao Y, Nakane T, Nakamae H, Shimono T, Hino M.
[Rinshō ketsueki] The Japanese journal of clinical hematology.Rinsho Ketsueki.2013 Apr;54(4):397-402.
A 20-year-old female presented with thirst, polyposia, and polyuria and was referred to our hospital because of leukocytosis and anemia. Bone marrow aspiration revealed 66.8% myeloperoxidase-positive blasts and trilineage myelodysplasia. The karyotype was 45, XX, inv(3)(q21q26.2), -7[19]. Therefore,
PMID 23666224

Central adrenal insufficiency and diabetes insipidus misdiagnosed as severe depression.

Hiroi N1, Yoshihara A, Sue M, Yoshino G, Higa M.
Clinical medicine insights. Case reports.Clin Med Insights Case Rep.2010;3:55-8. Epub 2010 Sep 27.
A 68 year-old Japanese man, who had been suffering from immobilization and disuse syndrome, was admitted to our hospital for evaluation of polyuria with polyposia, hyponatremia and low blood pressure. His plasma osmolality was greater than that of his urine. His endocrinological examination revealed
PMID 21769255

Satoh K1, Narita T, Matsui-Inohara H, Ito T, Senpuku H, Sugiya H.
The journal of medical investigation : JMI.J Med Invest.2009;56 Suppl:260-1.
Saliva contains a wide variety of secretory proteins, including alpha-amylase, lysozyme, peroxidase, immunoglobulins, and mucins. Hyposecretion of saliva and consequent dry mouth will lead to severe dental caries, periodontal disease, and mucosal infections, resulting in degrade of quality of life.
PMID 20224195