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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/01/29 09:19:36」(JST)
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Hexadimethrine bromide |
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IUPAC name
1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide
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Identifiers |
CAS number |
28728-55-4 Y |
Properties |
Molecular formula |
(C13H30Br2N2)n, linear form |
Molar mass |
variable |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa) |
Infobox references |
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Hexadimethrine bromide (Polybrene) is a cationic polymer used to increase the efficiency of infection of certain cells with a retrovirus in cell culture. Polybrene acts by neutralizing the charge repulsion between virions and sialic acid on the cell surface.[1] It has other uses, including a role in protein sequencing.
The IUPAC name for hexadimethrine bromide is 1,5-dimethyl-1,5-diazaundecamethylene polymethobromide.
References
- ^ Howard E. Davis, Matthew Rosinski , Jeffrey R. Morgan and Martin L. Yarmush, et al. (2004). "Charged Polymers Modulate Retrovirus Transduction via Membrane Charge Neutralization and Virus Aggregation.". Biophysical Journal 86 (2): 1234–42. doi:10.1016/S0006-3495(04)74197-1. PMC 1303915. PMID 14747357.
English Journal
- Dynamically formed admicelle layer to control the amplitude of cathodic electroosmotic flow.
- Erny GL, Gonçalves BM, Esteves VI.SourceCESAM & Department of Chemistry, University of Aveiro, Campus de Santiago, 3810-193 Aveiro, Portugal.
- Journal of chromatography. A.J Chromatogr A.2012 Sep 21;1256:271-5. Epub 2012 Jul 31.
- In this manuscript, a method to precisely adjust the amplitude of a cathodic electroosmotic flow is described. The method uses a capillary pre-coated with a cationic polymer (polybrene), in presence of an anionic surfactant such as sodium dodecyl sulfate. At low concentration of surfactant, molecule
- PMID 22901301
- High efficiency joint CZE determination of sugars and acids in vegetables and fruits.
- Cebolla-Cornejo J, Valcárcel M, Herrero-Martínez JM, Roselló S, Nuez F.SourceInstituto Universitario de Conservación y Mejora de la Agrodiversidad Valenciana (COMAV), Universitat Politècnica de València, València, Spain.
- Electrophoresis.Electrophoresis.2012 Aug;33(15):2416-23. doi: 10.1002/elps.201100640.
- In this work, an improved CE method for the medium-throughput determination of main organic acids (oxalate, malate, citrate), the amino acid glutamate and the sugars fructose, glucose and sucrose in several food matrices is described. These compounds have been identified as key components in the tas
- PMID 22887163
Japanese Journal
- Effects of Unripe Citrus hassaku Fruits Extract and Its Flavanone Glycosides on Blood Fluidity
- Itoh Kimihisa,Masuda Megumi,Naruto Shunsuke,Murata Kazuya,Matsuda Hideaki
- Biological & Pharmaceutical Bulletin 33(4), 659-664, 2010
- … CH-ext concentration-dependently inhibited in vitro collagen-induced rabbit platelet aggregation and in vitro polybrene-induced rat erythrocyte aggregation. …
- NAID 130000248015
- Separation of complex mixtures of fluorobenzoic acids by capillary electrophoresis
- Isemura Tsuguhide,Kitagawa Fumihiko,Otsuka koji
- 旭硝子研究報告 59, 98-104, 2009
- NAID 40016972225
Related Links
- Polybreneの最適濃度は細胞種に依存します。経験的に決定してください(通常は2-10μg/mLの範囲です)。過度のPolybreneへの暴露(12時間以上 ...
- Polybrene ® sc-134220 ... 1 ml; 10mg/ml in sterile water highly efficient infection reagent used to introduce retroviral vectors into mammalian cells also known as hexamethrine bromide, 1,5-Dimethyl-1,5-diazaundecamethylene ...
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