English Journal

Experimental phase diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence.

Vlijm R1, Mashaghi A, Bernard S, Modesti M, Dekker C.
Nanoscale.Nanoscale.2015 Feb 21;7(7):3205-16. doi: 10.1039/c4nr04332d.
The most common form of DNA is the well-known B-structure of double-helix DNA. Many processes in the cell, however, exert force and torque, inducing structural changes to the DNA that are vital to biological function. Virtually all DNA in cells is in a state of negative supercoiling, with a DNA stru
PMID 25615283

Double-stranded RNA under force and torque: similarities to and striking differences from double-stranded DNA.

Lipfert J1, Skinner GM2, Keegstra JM2, Hensgens T2, Jager T2, Dulin D2, Köber M2, Yu Z2, Donkers SP2, Chou FC3, Das R4, Dekker NH5.
Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2014 Oct 28;111(43):15408-13. doi: 10.1073/pnas.1407197111. Epub 2014 Oct 13.
RNA plays myriad roles in the transmission and regulation of genetic information that are fundamentally constrained by its mechanical properties, including the elasticity and conformational transitions of the double-stranded (dsRNA) form. Although double-stranded DNA (dsDNA) mechanics have been diss
PMID 25313077

Coexistence of twisted, plectonemic, and melted DNA in small topological domains.

Meng H1, Bosman J1, van der Heijden T1, van Noort J2.
Biophysical journal.Biophys J.2014 Mar 4;106(5):1174-81. doi: 10.1016/j.bpj.2014.01.017.
DNA responds to small changes in force and torque by over- or undertwisting, forming plectonemes, and/or melting bubbles. Although transitions between either twisted and plectonemic conformations or twisted and melted conformations have been described as first-order phase transitions, we report here
PMID 24606941

Japanese Journal

Viewing of Complex Molecules of Ethidium Bromide and Plasmid DNA in Solution by Atomic Force Microscopy

Utsuno Kuniharu,Tsuboi Masamichi,Katsumata Shunji [他],IWAMOTO Toschitake
Chemical & pharmaceutical bulletin 49(4), 413-417, 2001-04-01
… The supercoiling always resulted in an interwound(or a plectonemic)form, but never a solenoidal(or a toroidal)form. …
NAID 110003615913