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- 1. 透析患者における消化管疾患 gastrointestinal disease in dialysis patients
English Journal
- Functional expression of a putative geraniol 8-hydroxylase by reconstitution of bacterially expressed plant CYP76F45 and NADPH-cytochrome P450 reductase CPR I from Croton stellatopilosus Ohba.
- Sintupachee S1, Promden W2, Ngamrojanavanich N3, Sitthithaworn W4, De-Eknamkul W5.
- Phytochemistry.Phytochemistry.2015 Oct;118:204-15. doi: 10.1016/j.phytochem.2015.08.005. Epub 2015 Aug 20.
- While attempting to isolate the enzyme geranylgeraniol 18-hydroxylase, which is involved in plaunotol biosynthesis in Croton stellatopilosus (Cs), the cDNAs for a cytochrome P450 monooxygenase (designated as CYP76F45) and an NADPH-cytochrome P450 reductase (designated as CPR I based on its classific
- PMID 26300313
- Molecular cloning, bacterial expression and functional characterisation of cytochrome P450 monooxygenase, CYP97C27, and NADPH-cytochrome P450 reductase, CPR I, from Croton stellatopilosus Ohba.
- Sintupachee S1, Ngamrojanavanich N2, Sitthithaworn W3, De-Eknamkul W4.
- Plant science : an international journal of experimental plant biology.Plant Sci.2014 Dec;229:131-41. doi: 10.1016/j.plantsci.2014.09.001. Epub 2014 Sep 16.
- The cDNAs for cytochrome P450 monooxygenase (designated as CYP97C27 by D. Nelson's group) and NADPH-cytochrome P450 reductase (designated as CPR I based on its classification) were isolated from Croton stellatopilosus leaves, which actively biosynthesise plaunotol (18-OH geranylgeraniol). CYP97C27 a
- PMID 25443840
- Molecular cloning and catalytic activity of a membrane-bound prenyl diphosphate phosphatase from Croton stellatopilosus Ohba.
- Nualkaew N1, Guennewich N, Springob K, Klamrak A, De-Eknamkul W, Kutchan TM.
- Phytochemistry.Phytochemistry.2013 Jul;91:140-7. doi: 10.1016/j.phytochem.2012.09.010. Epub 2012 Oct 22.
- Geranylgeraniol (GGOH), a bioactive acyclic diterpene with apoptotic induction activity, is the immediate precursor of the commercial anti-peptic, plaunotol (18-hydroxy geranylgeraniol), which is found in Croton stellatopilosus (Ohba). From this plant, a cDNA encoding a prenyl diphosphate phosphatas
- PMID 23092673
Japanese Journal
- Anti-inflammatory activity of diterpenes from Croton stellatopilosus on LPS-induced RAW264.7 cells
- Premprasert Charoenwong,Tewtrakul Supinya,Plubrukarn Anuchit [他],WUNGSINTAWEEKUL Juraithip
- Journal of natural medicines 67(1), 174-181, 2013-01-01
- NAID 10031131615
- Protective effect of plaunotol against doxorubicin-induced renal cell death
- Chaotham Chatchai,De-Eknamkul Wanchai,Chanvorachote Pithi
- Journal of natural medicines 67(2), 311-319, 2013
- NAID 40019609052
- Nickel/Lewis Acid-Catalyzed Carbocyanation of Unsaturated Compounds
- Nakao Yoshiaki
- Bulletin of the Chemical Society of Japan 85(7), 731-745, 2012-07-15
- … The high chemo-, regio-, and stereoselectivities of the alkyne–carbocyanation reactions were highlighted by the syntheses of biologically active compounds including the synthetic precursor of P-3622 and plaunotol, which possess defined tri- or tetrasubstituted ethene structures. …
- NAID 10030785527
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