English Journal
- Platonin mitigates acute lung injury induced by bilateral lower limb ischemia-reperfusion in rats.
- Hsu KY, Tsai PS, Lee JJ, Wang TY, Huang CJ.SourceDepartment of Anesthesiology, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei, Taiwan; School of Medicine, Tzu Chi University, Hualien, Taiwan.
- The Journal of surgical research.2011 May 15;167(2):e255-62. Epub 2010 Apr 24.
- PMID 20472255
- Platonin Inhibits Endotoxin-Induced MAPK and AP-1 Up-Regulation.
- Lee JJ, Liu CL, Tsai PS, Yang CL, Lao HC, Huang CJ.SourceDepartment of Surgery, Mackay Memorial Hospital, Taipei, Taiwan; Department of Pharmacology, Taipei Medical University, Taipei, Taiwan.
- The Journal of surgical research.2011 May 15;167(2):e299-305. Epub 2009 Dec 22.
- PMID 20338586
Japanese Journal
- Platonin, a Cyanine Photosensitizing Dye, Inhibits Pyrogen Release and Results in Antipyresis
- LEE Jie-Jen,HUANG Wu-Tein,SHAO Dong-Zi,LIAO Jyh-Fei,LIN Mao-Tsun
- Journal of pharmacological sciences 93(3), 376-380, 2003-11-01
- … When incubating the platonin with the LPS-human PBMC, both the levels of IL-1β, IL-6, or TNF-α in supernatant fluids and the pyrogenicity of supernatant fluids were significantly suppressed. … In addition, both the fever and the increased levels of either IL-1β, IL-6, or TNF-α in rabbit serum following an intravenous administration of LPS were significantly attenuated by pretreatment with an intravenous dose of platonin. …
- NAID 130000073931
- Platonin, a Photosensitizing Dye, Improves Circulatory Failure and Mortality in Rat Models of Endotoxemia
- HSIAO George,LFE Ji-Jen,CHOU Duen-Suey,FONG Tsorng-Harn,SHEN Ming-Yi,LIN Chien-Huang,SHEU Joen-Rong
- Biological & pharmaceutical bulletin 25(8), 995-999, 2002-08-01
- … Platonin, a cyanine photosensitizing dye, is a potent macrophage-activating agent and an immunomodulator. … In this study, we compare the inhibitory effects of platonin with those of the three clinical drugs minocycline, clindamycin, and cyclosporin, on hypotension, tachycardia, and nitric oxide (NO) formation in a rat model of circulatory shock induced by Escherichia coli lipopolysaccharide (LPS). …
- NAID 110003638862
Related Links
- Platonin, a cyanine photosensitizing dye, is a potent macrophage-activating agent and an immunomodulator. In this study, we compare the inhibitory effects of platonin with those of the three clinical drugs minocycline, clindamycin ...
- ... either interleukin-1β (IL-1β), IL-6, or tumor necrosis factor-α (TNF-α) in supernatant fluids. When incubating the platonin with the LPS-human PBMC, both the levels of IL-1β, IL-6, or TNF-α in supernatant fluids and the Journal of ...
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★リンクテーブル★
| リンク元 | 「プラトニン」 |
「プラトニン」
- 英
- platonin
- 抗菌や創傷治癒の目的で使用される感光色素
- 熱傷及び難治性皮膚潰瘍の治癒促進に対して効能効果を持つ医療用医薬品
- 組織細胞機能用医薬品
- 細胞賦活用薬
- 色素製剤
- 感光色素製剤
- 化粧品に入っているらしい
概念
- 感光素は、もともと写真の感光膜の感光度を高める性能を持つ物質。シアニン系の色素で、青緑色の結晶性粉末で、においはなく、特異な味がある。
性質
- 化粧品としては、抗菌作用が強く、皮膚の洗浄、保護、整肌目的に使用される。
- 医薬品としては、白血球貧食作用促進、外科的疾患の治療に使用される。
- 無刺激抗菌剤として、0,002%以下の濃度で用いられる。
化粧品への配合
- クリーム、乳液、化粧水、天花粉、石けんなど
参考文献
- 感光素101号