English Journal

Yang Z, Vadlamudi RK, Kumar R.SourceDepartment of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
The Journal of biological chemistry.J Biol Chem.2005 Jan 7;280(1):654-9. Epub 2004 Oct 24.
Recent studies have identified dynein light chain-1 (DLC1), a component of the dynein motor, as a p21-activated kinase 1 (Pak1)-interacting substrate with binding sites mapped to amino acids 61-89 of DLC1 and phosphorylation site at serine 88. Here we investigated the role of DLC1 phosphorylation by
PMID 15504720

Membrane retrieval in neutrophils during phagocytosis: inhibition by M protein-expressing S. pyogenes bacteria.

Bauer S, Tapper H.SourceSection for Molecular Pathogenesis, Department of Cell and Molecular Biology, BMC, B14, Lund University, Tornavägen 10, SE-221 84 Lund, Sweden.
Journal of leukocyte biology.J Leukoc Biol.2004 Dec;76(6):1142-50. Epub 2004 Aug 31.
During phagocytosis and phagosome maturation, complex membrane traffic events must be coordinated. We have observed, using fluorescent fluid-phase and membrane markers, that in the human neutrophil, internalization of nonopsonized, Gram-positive bacteria, but not of latex beads, is accompanied by a
PMID 15339937

Annexin 2 binding to phosphatidylinositol 4,5-bisphosphate on endocytic vesicles is regulated by the stress response pathway.

Hayes MJ, Merrifield CJ, Shao D, Ayala-Sanmartin J, Schorey CD, Levine TP, Proust J, Curran J, Bailly M, Moss SE.SourceDivision of Cell Biology, Institute of Ophthalmology, University College London, 11-43 Bath Street, London EC1V 9EL, United Kingdom.
The Journal of biological chemistry.J Biol Chem.2004 Apr 2;279(14):14157-64. Epub 2004 Jan 20.
Annexin 2 is a Ca(2+)-binding protein that has an essential role in actin-dependent macropinosome motility. We show here that macropinosome rocketing can be induced by hyperosmotic shock, either alone or synergistically when combined with phorbol ester or pervanadate. Rocketing was blocked by inhibi
PMID 14734570

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