English Journal
- Palladium-catalyzed phthalazinone synthesis using paraformaldehyde as carbon source.
- Wang H1, Cai J, Huang H, Deng GJ.
- Organic letters.Org Lett.2014 Oct 17;16(20):5324-7. doi: 10.1021/ol502498y. Epub 2014 Sep 29.
- A palladium-catalyzed one-pot synthesis of phthalazinones from 2-halomethyl benzoates, paraformaldehyde, and aryl hydrazines is described. Various substituted phthalazinones were selectively obtained in good yields using paraformaldehyde as the cheap carbon source (CH).
- PMID 25265212
- Synthesis of phthalazinones via palladium(II)-catalysed intramolecular oxidative C-H/C-H cross-coupling of N'-methylenebenzohydrazides.
- Matsuda T1, Tomaru Y, Matsuda Y.
- Organic & biomolecular chemistry.Org Biomol Chem.2013 Apr 7;11(13):2084-7. doi: 10.1039/c3ob40195b.
- A palladium(II)-catalysed intramolecular oxidative C-H/C-H cross-coupling of N'-methylenebenzohydrazides to phthalazin-1(2H)-ones has been developed. This cyclization is believed to mechanistically proceed via electrophilic ortho-palladation and subsequent C-arylation of the carbon-nitrogen double b
- PMID 23440090
Japanese Journal
- Practical synthesis of new chiral cis-phthalazinones with potential for high phosphodiesterase (PDE4) inhibitory activity
- Dang Tinh Van,Jin Chung Keun,Miyamoto Motoyuki [他],Ikee Yoshifumi,Masuda Takashi,Sano Shigeki,Shiro Motoo,Nagao Yoshimitsu
- HETEROCYCLES 68(10), 2133-2144, 2006-10-01
- NAID 40007452361
- Novel Antiasthematic Agents with Dual Activities of Thromboxane A_2 Synthetase Inhibition and Bronchodilation. IV.2-[2-(1-Imidazolyl)ethyl]-4-(3-pyridyl-1(2H)-phthalazinones
- 山口 雅久,古賀 隆樹,亀井 研志,秋間 通立,丸山 典昭,黒木 俊夫,濱名 政和,大井 信広
- Chemical & pharmaceutical bulletin 42(9), 1850-1853, 1994-09-15
- … Synthesis and pharmacological evaluation of several compounds related to 2-[2-(1-imidazolyl)ethyl]-4-(3-pyridyl)-1(2H)-phthalazinones are described. …
- NAID 110003631246
Related Links
- Synthesis and pharmacological evaluation of several compounds related to 2-[2-(1-imidazolyl)ethyl]-4-(3-pyridyl)-1(2H)-phthalazinones are described. The phenyl moiety of the phthalazinone skeleton was found to play an important role ...
- Synthesis and pharmacological evaluation of several compounds related to 2-[2-(1-imidazolyl)ethyl]-4-(3-pyridyl)-1(2H)-phthalazinones are described. The phenyl moiety of the phthalazinone skeleton was found to play an important role ...
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