English Journal

TRAF3IP2 mediates interleukin-18-induced cardiac fibroblast migration and differentiation.

Valente AJ, Sakamuri SS, Siddesha JM, Yoshida T, Gardner JD, Prabhu R, Siebenlist U, Chandrasekar B.SourceMedicine, University of Texas Health Science Center and South Texas Veterans Health Care System, San Antonio, TX 78229, United States.
Cellular signalling.Cell Signal.2013 Nov;25(11):2176-84. doi: 10.1016/j.cellsig.2013.07.013. Epub 2013 Jul 18.
TRAF3IP2 is a cytoplasmic adapter protein and an upstream regulator of IKK/NF-κB and JNK/AP-1. Here we demonstrate for the first time that the proinflammatory cytokine interleukin (IL)-18 induces TRAF3IP2 expression in primary cardiac fibroblasts (CF) in a Nox4/hydrogen peroxide-dependent manner. S
PMID 23872479

Full-length single-stranded PCR product mediated chromosomal integration in intact Bacillus subtilis.

Wen S, Yang J, Tan T.SourceBeijing Key Laboratory of Bioprocess, The Biorefinery Research and Engineering Center of the Ministry of Education of China, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, PR China.
Journal of microbiological methods.J Microbiol Methods.2013 Mar;92(3):273-7. doi: 10.1016/j.mimet.2012.11.012. Epub 2012 Nov 28.
The research introduced a novel method for gene replacement in intact Bacillus subtilis by employing full-length single-stranded (ss) DNA constructs and electro-transformation. 5' phosphorothioated lagging-strand targeting ssDNA construct was demonstrated to be highly recombinogenic, and the utility
PMID 23201169

Therapeutic effect of ribbon-type nuclear factor-κB decoy oligonucleotides in a rat model of inflammatory bowel disease.

Ozaki K, Makino H, Aoki M, Miyake T, Yasumasa N, Osako MK, Nakagami H, Rakugi H, Morishita R.SourceDepartment of Clinical Gene Therapy, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita 565-0871, Japan.
Current gene therapy.Curr Gene Ther.2012 Dec;12(6):484-92.
BACKGROUND: The pathogenesis of inflammatory bowel disease (IBD) involves local expression of inflammatory cytokines, some of which are coordinated by nuclear factor-κB (NF-κB). Several reports documented the therapeutic potential of double-stranded phosphorothioated decoy oligonucleotides (S-ODNs
PMID 23061565

Japanese Journal

Time Course of Changes in μ-Opioid Receptor mRNA Levels in the Periaqueductal Gray of Rat Brain by a Single or Repeated Injections of Antisense Oligodeoxynucleotides

Yoshikawa Masanobu,Yokogami Kouichi,Kitamura Ken [他],KOBAYASHI Tomomi,KANAI Masayuki,TANIGUCHI Takao,AKAHORI Kazuhito,NAKABAYASHI masaru,IWAO Kayoko,HYODO Masao,OKA Tetsuo
The Japanese journal of pharmacology 81(2), 209-215, 1999-10-00
… The effect of phosphorothioated antisense oligodeoxynucleotide (AS ODN) against the μ-opioid receptor (MOR) on MOR mRNA level in the periaqueductal gray (PAG) of rat brain was investigated. …
NAID 10008196917