phosphohexokinase

English Journal

Differential regulation of the expression of lipid metabolism-related genes with skeletal muscle type in growing chickens.

Saneyasu T1, Kimura S1, Kitashiro A1, Tsuchii N1, Tsuchihashi T1, Inui M1, Honda K1, Kamisoyama H1.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.Comp Biochem Physiol B Biochem Mol Biol.2015 Nov;189:1-5. doi: 10.1016/j.cbpb.2015.07.002. Epub 2015 Jul 15.
The regulatory mechanisms of carbohydrate and lipid metabolism are known to differ among skeletal muscle types in mammals. For example, glycolytic muscles prefer glucose as an energy source, whereas oxidative muscles prefer fatty acids (FA). We herein demonstrated differences in the expression of ge
PMID 26188321

Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation.

Kloos M1, Brüser A2, Kirchberger J2, Schöneberg T2, Sträter N3.
The Biochemical journal.Biochem J.2015 Aug 1;469(3):421-32. doi: 10.1042/BJ20150251. Epub 2015 Jun 11.
Phosphofructokinase-1 (Pfk) acts as the main control point of flux through glycolysis. It is involved in complex allosteric regulation and Pfk mutations have been linked to cancer development. Whereas the 3D structure and structural basis of allosteric regulation of prokaryotic Pfk has been studied
PMID 26205495

Resveratrol increases glycolytic flux in Saccharomyces cerevisiae via a SNF1-dependet mechanism.

Madrigal-Perez LA1, Nava GM, González-Hernández JC, Ramos-Gomez M.
Journal of bioenergetics and biomembranes.J Bioenerg Biomembr.2015 Aug;47(4):331-6. doi: 10.1007/s10863-015-9615-y. Epub 2015 Jun 20.
Evidence suggests that AMP protein kinase (AMPK) is the main target of the phytochemical resveratrol (RSV) in mammalian cells. Data also indicates that RSV stimulates glucose metabolism; however, the molecular link between RSV and glucose uptake remains unknown. Herein, we provide evidence indicatin
PMID 26091703