フェニルビグアニド
English Journal
- Modulation of Cardiopulmonary Depressor Reflex in Nucleus Ambiguus by Electroacupuncture: Roles of Opioids and Gamma Aminobutyric Acid.
- Tjen-A-Looi SC, Li P, Li M, Longhurst JC.Source1University of California, Irvine.
- American journal of physiology. Regulatory, integrative and comparative physiology.Am J Physiol Regul Integr Comp Physiol.2011 Dec 28. [Epub ahead of print]
- Stimulation of cardiopulmonary receptors with phenylbiguanide (PBG) elicits depressor cardiovascular reflex responses, including decreases in blood pressure and heart rate mediated by the brainstem parasympathetic cardiac neurons in the nucleus ambiguus (NAmb). The present study examined NAmb neurot
- PMID 22204951
- The effects of catalase inhibition into the fourth cerebral ventricle on the Bezold-Jarisch reflex in spontaneously hypertensive rats.
- Cisternas JR, Valenti VE, Sato MA, Fonseca FL, Saldiva PH, De Mello Monteiro CB, Neto ML, Rodrigues LM, De Abreu LC.SourceLaboratório de Escrita Científica, Departamento de Morfologia e Fisiologia, Faculdade de Medicina do ABC, Santo André, SP, Brasil. raulcisternas@terra.com.br.
- Journal of integrative neuroscience.J Integr Neurosci.2011 Dec;10(4):475-87.
- Many studies have investigated the role of oxidative stress on cardiovascular system in the brainstem of spontaneously hypertensive rats (SHR). However, we do not know yet if catalase inhibition influences cardiopulmonary reflex (Bezol-Jarisch reflex). Thus, we aimed to evaluate the effects of centr
- PMID 22262536
- Chronic hypoxic incubation blunts a cardiovascular reflex loop in embryonic American alligator (Alligator mississippiensis).
- Eme J, Hicks JW, Crossley DA 2nd.SourceDepartment of Biological Sciences, University of North Texas, 1155 Union Circle, PO Box 305220, Denton, TX, 76203-5017, USA. johneme34@gmail.com
- Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology.J Comp Physiol B.2011 Oct;181(7):981-90. Epub 2011 Mar 29.
- Hypoxia is a naturally occurring environmental challenge for embryonic non-avian reptiles, and this study is the first to investigate the impact of chronic hypoxia on a possible chemoreflex loop in a developing non-avian reptile. We measured heart rate and blood pressure in normoxic and hypoxic-incu
- PMID 21445563
Japanese Journal
- Bezold-Jarisch Reflex Blunts Arterial Baroreflex via the Shift of Neural Arc toward Lower Sympathetic Nerve Activity
- KASHIHARA K.,KAWADA T.,LI MEIHUA,SUGIMACHI M.,SUNAGAWA K.
- The Japanese journal of physiology 54(4), 395-404, 2004-08-03
- NAID 10014089776
- 2-Methyl-5-HT-Induced Vasoconstrictions Mediated via α<SUB>1</SUB>-Adrenoceptors in Rabbit Common Carotid Arteries
- Fujiwara Toshimasa,Chiba Shigetoshi
- The Japanese Journal of Pharmacology 66(1), 155-157, 1994
- … We investigated the effects of 2-methyl-5-HT and 1-phenylbiguanide on isolated and perfused rabbit common carotid arteries by a cannula insertion method. … 1-Phenylbiguanide produced neither vasoconstriction nor dilation. …
- NAID 130000840655
- Activation of 5-HT_3receptor by 1-phenylbiguanide increases dopamine release in the rat nucleus accumbens
Related Links
- 13 Aug 1998 ... Phenylbiguanide (PBG), a 5-HT3 (serotonin) receptor agonist, has been used in many studies as a “selective” agonist to elicit reflex bradycardia and hypotension through activation of cardiac and pulmonary vagal afferents.
- View and buy high purity 1-Phenylbiguanide hydrochloride from Tocris Bioscience, the leading worldwide supplier of high performance life science reagents.
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