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Periostitis, also known as periostalgia, is a medical condition caused by inflammation of the periosteum, a layer of connective tissue that surrounds bone.^[1] The condition is generally chronic, and is marked by tenderness and swelling of the bone and an aching pain.

Causes [edit]

Acute periostitis is due to infection, is characterized by diffuse formation of pus, severe pain, constitutional symptoms, and usually results in necrosis. It can be caused by excessive physical activity as well, as in the case of medial tibial stress syndrome (also referred to as tibial periostalgia, soleus periostalgia, or shin splints). Congenital infection with syphilis can also cause periostitis in newborn infants.

Fossil record [edit]

Evidence for periostitis found in the fossil record is studied by paleopathologists, specialists in ancient disease and injury. Periostitis has been seen in the late Cretaceous-Eocene crocodile Borealosuchus formidabilis, once known as Leidyosuchus. In one study, periostitis was the most common pathology in this species, with 134 instances of the condition out of 7,154 bones the scientists examined showing evidence for the condition. Periostitis has also been documented in dinosaurs, including a forelimb referred to the long-necked Camarasaurus grandis, as well as the shoulder blade of a horned dinosaur.^[2]

References [edit]

^ Aufderheide, Arthur C.; Rodriguez-Martin, Conrado; Langsjoen, Odin M. (1998), The Cambridge Encyclopedia of Human Paleopathology, Cambridge University Press, pp. 179–181, ISBN 0521552036.
^ McWhinney, L.; Carpenter, K.; Rothschild, B. (2001), "Dinosaurian humeral periostitis: a case of a juxtacortical lesion in the fossil record", in Tanke, D. H.; Carpenter, K., Mesozoic Vertebrate Life (Indiana University Press): 364–377, ISBN 0253339073.

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English Journal

Primary hypertrophic osteoarthropathy: ultrasound and MRI findings.

Adams B1, Amin T2, Leone V2, Wood M2, Kraft JK3.
Pediatric radiology.Pediatr Radiol.2016 Mar 3. [Epub ahead of print]
Primary hypertrophic osteoarthropathy is a rare genetic disorder related to failures in prostaglandin metabolism. Patients present with joint pain, limb enlargement, skin thickening and finger clubbing. Radiographs show characteristic periosteal reaction and thickening along the long bones. We prese
PMID 26939972

Correlation of Pain and Fluoride Concentration in Allogeneic Hematopoietic Stem Cell Transplant Recipients on Voriconazole.

Barajas MR1, McCullough KB2, Merten JA3, Dierkhising RA4, Bartoo GT2, Hashmi SK5, Hogan WJ5, Litzow MR5, Patnaik MM5, Wilson JW6, Wolf RC2, Wermers RA7.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.Biol Blood Marrow Transplant.2016 Mar;22(3):579-83. doi: 10.1016/j.bbmt.2015.10.021. Epub 2015 Oct 31.
Supportive care guidelines recommend antimold prophylaxis in hematopoietic stem cell transplant (HSCT) recipients deemed to have high risk for invasive fungal infection, leading to long-term use of voriconazole after allogeneic HSCT in patients who remain immunocompromised. Voriconazole has been ass
PMID 26524731

Evaluation of Periapical Lesions and Their Association with Maxillary Sinus Abnormalities on Cone-beam Computed Tomographic Images.

Nunes CA1, Guedes OA2, Alencar AH1, Peters OA3, Estrela CR2, Estrela C4.
Journal of endodontics.J Endod.2016 Jan;42(1):42-6. doi: 10.1016/j.joen.2015.09.014. Epub 2015 Oct 29.
INTRODUCTION: Periapical inflammation is often responsible for distinct maxillary sinus (MS) changes. This retrospective, cross-sectional study evaluated the association between the clinical characteristics of periapical lesions (presence, size, and distance) in maxillary posterior teeth and the pre
PMID 26521148

Japanese Journal

原因不明の骨膜・骨間膜炎により前腕回内外制限をきたした1例

古屋佑樹,児玉成人,松末吉隆
中部日本整形外科災害外科学会雑誌. 中部日本整形外科災害外科学会抄録 54(6), 1295-1296, 2011-11-01
NAID 10030185610

強い炎症所見を呈し悪性腫瘍と鑑別を要した florid reactive periostitis の1例

荻原弘晃,牧野絵巳
中部日本整形外科災害外科学会雑誌. 中部日本整形外科災害外科学会抄録 54(1), 49-50, 2011-01-01
NAID 10029071162

Hypertrophic osteoarthropathy manifested with isolated calcaneal periostitis in bone scintigraphy

MORALIDIS Efstratios,GERASIMOU Georgios,THEODORIDOU Athina,HILIDIS Ilias,MYLONAKI Efrosyni,GOTZAMANI-PSARRAKOU Anna
Annals of nuclear medicine 24(4), 313-317, 2010-05-01
NAID 10026509260

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「骨膜炎」

Periostitis
	Classification and external resources
ICD-10	M90.1
ICD-9	730
DiseasesDB	29059
MeSH	D010522

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英: periostitis
関: 骨膜

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periosteitis 骨膜炎 : 23 件
periostitis 骨膜炎 : 約 1,730 件

[CEHP1998-1] Aufderheide, Arthur C.; Rodriguez-Martin, Conrado; Langsjoen, Odin M. (1998), The Cambridge Encyclopedia of Human Paleopathology, Cambridge University Press, pp. 179–181, ISBN 0521552036.

[dino-peri-2] McWhinney, L.; Carpenter, K.; Rothschild, B. (2001), "Dinosaurian humeral periostitis: a case of a juxtacortical lesion in the fossil record", in Tanke, D. H.; Carpenter, K., Mesozoic Vertebrate Life (Indiana University Press): 364–377, ISBN 0253339073.

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periostitis