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1. アルコール性肝疾患の病因 pathogenesis of alcoholic liver disease
2. 血管浮腫の概要：病因と原因 an overview of angioedema pathogenesis and causes
3. 細菌性髄膜炎の病因および病態生理 pathogenesis and pathophysiology of bacterial meningitis
4. 成人における慢性膵炎の病因および発症機序 etiology and pathogenesis of chronic pancreatitis in adults
5. 重症筋無力症の病因 pathogenesis of myasthenia gravis

English Journal

Tolvaptan for hyponatremia with preserved sodium pool in critically ill patients.

Umbrello M1,2, Mantovani ES3, Formenti P4, Casiraghi C5, Ottolina D6, Taverna M7, Pezzi A8, Mistraletti G9,10, Iapichino G11,12.
Annals of intensive care.Ann Intensive Care.2016 Dec;6(1):1. doi: 10.1186/s13613-015-0096-2. Epub 2016 Jan 4.
BACKGROUND: Hyponatremia is the most common electrolyte disturbance in hospitalized patients, and it represents a well-established risk factor for ICU/hospital mortality. The majority of hyponatremic states are associated with elevated arginine vasopressin levels and a preserved sodium pool. Convent
PMID 26728593

Sabirov RZ1,2, Merzlyak PG3,4, Islam MR3, Okada T3, Okada Y5,6.
Pflugers Archiv : European journal of physiology.Pflugers Arch.2016 Jan 6. [Epub ahead of print]
The maxi-anion channels (MACs) with a unitary conductance of 200-500 pS are detected in virtually every part of the whole body and found in cells from mammals to amphibia. The channels are normally silent but can be activated by physiologically/pathophysiologically relevant stimuli, such as osmotic
PMID 26733413

Neural Correlates of Three Promising Endophenotypes of Depression: Evidence from the EMBARC Study.

Webb CA1, Dillon DG1, Pechtel P1, Goer FK1, Murray L1, Huys QJ2,3, Fava M4, McGrath PJ5, Weissman M5, Parsey R6, Kurian BT7, Adams P5, Weyandt S7, Trombello JM7, Grannemann B7, Cooper CM7, Deldin P8, Tenke C5, Trivedi M7, Bruder G5, Pizzagalli DA1.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.Neuropsychopharmacology.2016 Jan;41(2):454-63. doi: 10.1038/npp.2015.165. Epub 2015 Jun 12.
Major depressive disorder (MDD) is clinically, and likely pathophysiologically, heterogeneous. A potentially fruitful approach to parsing this heterogeneity is to focus on promising endophenotypes. Guided by the NIMH Research Domain Criteria initiative, we used source localization of scalp-recorded
PMID 26068725

Molecular Pathopharmacology of 5-HT_<2C> Receptors and the RNA Editing in the Brain

TOHDA Michihisa,NOMURA Michio,NOMURA Yasuyuki
Journal of pharmacological sciences 100(5), 427-432, 2006-05-15
… Among the 14 kinds of serotonin (5-hydroxytryptamine, 5-HT) receptor subtypes (5-HTR), 5-HT2C receptor (5-HT2CR) has been intensively investigated because of its physiologically and pathophysiologically important role in the brain. …
NAID 10018238768