Central activating transcription factor 4 (ATF4) regulates hepatic insulin resistance in mice via S6K1 signaling and the vagus nerve.
Zhang Q, Yu J, Liu B, Lv Z, Xia T, Xiao F, Chen S, Guo F.SourceKey Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China.
Diabetes.Diabetes.2013 Jul;62(7):2230-9. doi: 10.2337/db12-1050. Epub 2013 Mar 1.
Recent studies have revealed that the central nervous system, particularly the hypothalamus, is critical for regulating insulin sensitivity in peripheral tissues. The aim of our current study is to investigate the possible involvement of hypothalamic activating transcription factor 4 (ATF4) in the r
The effect of exogenous GLP-1 on food intake is lost in male truncally vagotomized subjects with pyloroplasty.
Plamboeck A, Veedfald S, Deacon CF, Hartmann B, Wettergren A, Svendsen LB, Meisner S, Hovendal C, Vilsbøll T, Knop FK, Holst JJ.SourceDiabetes Research Division, Department of Internal Medicine, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark. astridp@sund.ku.dk
American journal of physiology. Gastrointestinal and liver physiology.Am J Physiol Gastrointest Liver Physiol.2013 Jun 15;304(12):G1117-27. doi: 10.1152/ajpgi.00035.2013. Epub 2013 Apr 18.
Rapid degradation of glucagon-like peptide-1 (GLP-1) by dipeptidyl peptidase-4 suggests that endogenous GLP-1 may act locally before being degraded. Signaling via the vagus nerve was investigated in 20 truncally vagotomized subjects with pyloroplasty and 10 matched healthy controls. Subjects receive
Aortocaval fistula delays gastric emptying of liquid test meal in awake rats.
Silva MT, Palheta RC Jr, Oliveira FG, de Lima JB, Antunes-Rodrigues J, Oliveira RB, Magalhães PJ, Santos AA.SourceDepartment of Physiology and Pharmacology, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
American journal of physiology. Heart and circulatory physiology.Am J Physiol Heart Circ Physiol.2013 May 15;304(10):H1397-405. doi: 10.1152/ajpheart.00827.2012. Epub 2013 Mar 15.
Arteriovenous anastomoses disrupt cardiovascular and renal homeostasis, eliciting hemodynamic adjustments, resetting the humoral pattern, and inducing cardiac hypertrophy. Because acute circulatory imbalance alters gut motor behavior, we studied the effects of arteriovenous fistula placement on the
Degradation of submandibular gland AQP5 by parasympathetic denervation of chorda tympani and its recovery by cevimeline, an M3 muscarinic receptor agonist
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 295(1), G112-G123, 2008
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