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extract from the pancreas of animals that contains pancreatic enzymes; used to treat pancreatitis and other conditions involving insufficient pancreatic secretions

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/05 15:34:08」(JST)

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Pancreatin is a mixture of several digestive enzymes produced by the exocrine cells of the pancreas. It is composed of amylase, lipase and protease. This mixture is used to treat conditions in which pancreatic secretions are deficient, such as surgical pancreatectomy, pancreatitis and cystic fibrosis. It has been claimed to help with food allergies, celiac disease, autoimmune disease, cancer and weight loss. Pancreatin is sometimes called "pancreatic acid", although it is neither a single chemical substance nor an acid.

Pancreatin contains the pancreatic enzymes trypsin, amylase and lipase. A similar mixture of enzymes is sold as pancrelipase, which contains more active lipase enzyme than does pancreatin. The trypsin found in pancreatin works to hydrolyze proteins into oligopeptides; amylase hydrolyzes starches into oligosaccharides and the disaccharide maltose; and lipase hydrolyzes triglycerides into fatty acids and glycerols. Pancreatin is an effective enzyme supplement for replacing missing pancreatic enzymes, and aids in the digestion of foods in cases of pancreatic insufficiency.

Pancreatin reduces the absorption of iron from food in the duodenum during digestion ^[1]

Some contact lens cleaning solutions contain porcine pancreatin extractives to assist in the intended protein-removal process.

References

^ R. Stephton Smith (1965) 'IRON DEFICIENCY AND IRON OVERLOAD' Arch. Dis. Childh. 40, 343.

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1. Total pancreatectomy

English Journal

Does boiling affect the bioaccessibility of selenium from cabbage?

Funes-Collado V1, Rubio R2, López-Sánchez JF3.
Food chemistry.Food Chem.2015 Aug 15;181:304-9. doi: 10.1016/j.foodchem.2015.02.052. Epub 2015 Feb 16.
The bioaccessible selenium species from cabbage were studied using an in vitro physiologically-based extraction test (PBET) which establishes conditions that simulate the gastric and gastrointestinal phases of human digestion. Samples of cabbage (Brassica oleracea) grown in peat fortified with diffe
PMID 25794754

Characterization and Comparison of Protein and Peptide Profiles and their Biological Activities of Improved Common Bean Cultivars (Phaseolus vulgaris L.) from Mexico and Brazil.

Mojica L1, de Mejía EG.
Plant foods for human nutrition (Dordrecht, Netherlands).Plant Foods Hum Nutr.2015 Jun;70(2):105-12. doi: 10.1007/s11130-015-0477-6.
Common bean (Phaseolus vulgaris L.) is a good source of protein, vitamins, minerals and complex carbohydrates. The objective was to compare protein profile, including anti-nutrient proteins, and potential bioactive peptides of improved common bean cultivars grown in Mexico and Brazil. Bean protein i
PMID 25764244

Neutralizing effect of hemolymph from the shore crab, Thalamita crenata, on paralytic shellfish toxins.

Lin H1, Zhang C2, Liao J3, Yang F4, Zhong S5, Jiang P6, Chen X7, Nagashima Y8.
Toxicon : official journal of the International Society on Toxinology.Toxicon.2015 Jun 1;99:51-7. doi: 10.1016/j.toxicon.2015.03.010. Epub 2015 Mar 19.
Several species of crabs are resistant to paralytic shellfish toxins (PSTs) and/or pufferfish toxin, tetrodotoxin, regardless of toxification by the toxins. The shore crab Thalamita crenata, which inhabits Leizhou Peninsula, China, is tolerant to PST toxicity, and the hemolymph has neutralizing effe
PMID 25797318

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