強皮症
WordNet
- of or relating to or characteristic of pachyderms (同)pachydermal, pachydermic, pachydermous
- any of various nonruminant hoofed mammals having very thick skin: elephant; rhinoceros; hippopotamus
PrepTutorEJDIC
- 厚皮動物(カバ・ゾウ・サイなど)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/02/05 22:33:49」(JST)
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Pachyderma |
Classification and external resources |
ICD-9-CM |
701.8 |
[edit on Wikidata]
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Pachyderma is the thickening of skin like that of a pachyderm.[1] It occurs in the condition Pachydermoperiostosis; an X-linked genetic disorder.[2]
References
- ^ "Definition of Pachyderma". MedicineNet.com. Retrieved 2008-04-06.
- ^ Castori M, Sinibaldi L, Mingarelli R, Lachman RS, Rimoin DL, Dallapiccola B (2005). "Pachydermoperiostosis: an update". Clin. Genet. 68 (6): 477–86. doi:10.1111/j.1399-0004.2005.00533.x. PMID 16283874.
English Journal
- Phylogenetic analyses of Coprinopsis sections Lanatuli and Atramentarii identify multiple species within morphologically defined taxa.
- Nagy LG, Desjardin DE, Vágvölgyi C, Kemp R, Papp T.SourceDepartment of Microbiology, University of Szeged, Szeged, Hungary. cortinarius2000@yahoo.co.uk
- Mycologia.Mycologia.2013 Jan-Feb;105(1):112-24. doi: 10.3852/12-136. Epub 2012 Oct 16.
- Sections Lanatuli and Atramentarii of the genus Coprinopsis contain some of the best known and most important agaric species, including C. cinerea and C. lagopus, yet a critical, phylogeny-based assessment of the species limits has not been carried out. Taxa have been characterized chiefly on the ba
- PMID 23074175
- Laryngeal and voice disorders in patients with gastroesophageal symptoms. Correlation with pH-monitoring.
- Martins RH, Branco A, Tavares EL, Iyomasa RM, Carvalho LR, Henry MA.SourceDivision of Otolaryngology, Department of Ophthalmology, Otolaryngology, Head and Neck Surgery, FMB, UNESP, Botucatu-SP, Brazil. rmartins@fmb.unesp.br
- Acta cirúrgica brasileira / Sociedade Brasileira para Desenvolvimento Pesquisa em Cirurgia.Acta Cir Bras.2012 Nov;27(11):821-8.
- PURPOSE: To investigate laryngeal and voice disorders in patients with gastroesophageal symptoms and their correlation with pH-monitoring.METHODS: A prospective study was carried out in patients attended at the Voice Disorder Outpatient Clinics of Botucatu Medical School in a five-year period and ha
- PMID 23117616
- Primary hypertrophic osteoarthropathy with digital clubbing and palmoplantar hyperhidrosis caused by 15-PGHD/HPGD loss-of-function mutations.
- Bergmann C, Wobser M, Morbach H, Falkenbach A, Wittenhagen D, Lassay L, Ott H, Zerres K, Girschick HJ, Hamm H.AbstractDigital clubbing is the most prominent feature in primary (PHO) and secondary (pulmonary) hypertrophic osteoarthropathy (HO). Homozygous and compound heterozygous germline mutations in the 15-hydroxyprostaglandin dehydrogenase (HPGD) gene encoding the major prostaglandin PGE2 catabolizing enzyme have been recently described in familial PHO cases. Elevated prostaglandin levels in affected individuals with cytokine-mediated tissue remodelling and vascular stimulation may underlie PHO and associated features as hyperhidrosis, acroosteolysis, pachyderma, periostosis and arthritis. We present clinical and biochemical data of three unrelated PHO families with HPGD mutations. The truncating mutation c.175_176del was found in two of our families and in one of the recently described pedigrees, all of European origin. We present evidence that c.175_176del is a recurrent mutation rather than an ancient founder allele. Two novel heterozygous HPGD mutations, the nonsense mutation c.118G>T (p.Glu40X) and the missense mutation c.563C>T (p.Thr188Ile), could be identified in a third family. We postulate that all HPGD mutations constitute loss-of-function alleles due to protein truncation or missense changes that affect hydrogen bonds lining the 15-PGDH enzyme reaction cavity. Elevated prostaglandin levels may give rise to use of non-steroidal anti-inflammatory drugs; however, therapeutic strategies have not been reported to date. Naproxen treatment in one of our mutation-positive patients resulted in alleviation of pain caused by periostosis and arthritis as well as reduction in substantially elevated prostaglandin levels, while no significant effects on digital clubbing, hyperhidrosis and pachyderma were observed. Further experience with nonsteroidal anti-inflammatory drugs in PHO is awaited.
- Experimental dermatology.Exp Dermatol.2011 Jun;20(6):531-3. doi: 10.1111/j.1600-0625.2011.01248.x. Epub 2011 Mar 23.
- Digital clubbing is the most prominent feature in primary (PHO) and secondary (pulmonary) hypertrophic osteoarthropathy (HO). Homozygous and compound heterozygous germline mutations in the 15-hydroxyprostaglandin dehydrogenase (HPGD) gene encoding the major prostaglandin PGE2 catabolizing enzyme hav
- PMID 21426412
Japanese Journal
- Seasonal variations in planktonic foraminiferal flux and oxygen isotopic composition in the western North Pacific : Implications for paleoceanographic reconstruction
- Sagawa Takuya,Kuroyanagi Azumi,Irino Tomohisa,Kuwae Michinobu,Kawahata Hodaka
- Marine Micropaleontology 100, 11-20, 2013-04
- … Six major species (Neogloboquadrina incompta, Nedgloboquadrina dutertrei, Neogloboquadrina pachyderma, Globigerina quinqueloba, Globigerina bulloides, and Globorotalia scitula) constituted 97% of the total foraminiferal flux. … pachyderma were observed in August. … pachyderma [sinistral (s)1 and with a -0.7% offset for N. … pachyderma (d). … pachyderma (s) and N. …
- NAID 120005317002
- 大場 忠道,谷村 好洋
- 地質学雑誌 118(6), 376-386, 2012
- … In this study, we compared the relative abundance of left-coiling specimens of a planktonic foraminiferal species (Neogloboquardrina pachyderma) in four sediment cores retrieved from the southern part of the Japan Sea with the horizontal distribution of left-coiling specimens in surface sediments of the northern part of the Japan Sea. …
- NAID 130001915325
- Neogloboquadrina pachydermaとNeogloboquadrina incomptaの古海洋学的意義(<特集>後期新生代の環境指標としての微古生物学と古海洋学の進展)
- 尾田 太良,堂満 華子
- 化石 (86), 6-11, 2009-10-16
- … As on of the most useful paleoceanographic proxies, the coiling direction of Neogloboquadrina pachyderma was widely used by many workers who have explained the behavior by temperature controlling the coiling direction in a single species. … pachyderma, with dominantly sinistral shells associated with rarely dextral forms. … pachyderma and N. …
- NAID 110007467295
Related Links
- pachyderma [pak″e-der´mah] abnormal thickening of the skin. adj., adj pachyder´matous. pachyderma circumscrip´tum (pachyderma laryn´gis) localized warty epithelial thickenings on the vocal cords. pach·y·der·ma (pak'ē-der'mă),
- Hyla robertsorum, pachyderma, and crassa are the most aquatic members of the group.
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