WordNet
- the 19th letter of the Roman alphabet (同)s
- an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
- the basic unit of money in Papua New Guinea
PrepTutorEJDIC
- sulfurの化学記号 / {略}South[ern]
UpToDate Contents
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- 1. 移植免疫 transplantation immunobiology
- 2. Physiology of insulin-like growth factor 1
- 3. 抗リボゾームP蛋白抗体 antiribosomal p protein antibodies
- 4. 小児における赤血球産生低下による貧血 anemia in children due to decreased red blood cell production
- 5. 骨髄異形成症候群における細胞遺伝学および分子遺伝学 cytogenetics and molecular genetics of myelodysplastic syndromes
English Journal
- Melanocortin 4 receptor activates ERK-cFos pathway to increase brain-derived neurotrophic factor expression in rat astrocytes and hypothalamus.
- Ramírez D1, Saba J1, Carniglia L1, Durand D1, Lasaga M1, Caruso C2.
- Molecular and cellular endocrinology.Mol Cell Endocrinol.2015 Aug 15;411:28-37. doi: 10.1016/j.mce.2015.04.008. Epub 2015 Apr 16.
- Melanocortins are neuropeptides with well recognized anti-inflammatory and anti-apoptotic effects in the brain. Of the five melanocortin receptors (MCR), MC4R is abundantly expressed in the brain and is the only MCR present in astrocytes. We have previously shown that MC4R activation by the α-melan
- PMID 25892444
- PMID 25889895
- ORF45-Mediated Prolonged c-Fos Accumulation Accelerates Viral Transcription during the Late Stage of Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus.
- Li X1, Du S2, Avey D3, Li Y2, Zhu F3, Kuang E4.
- Journal of virology.J Virol.2015 Jul 1;89(13):6895-906. doi: 10.1128/JVI.00274-15. Epub 2015 Apr 22.
- Kaposi's sarcoma-associated herpesvirus (KSHV) encodes multiple viral proteins that activate extracellular signal-regulated kinase (ERK)-mitogen-activated protein kinase (MAPK) cascades. One of these viral proteins, ORF45, mediates sustained ERK-p90 ribosomal S6 kinase (RSK) activation during KSHV l
- PMID 25903346
Japanese Journal
- Nicotinamide Prevents the Down-Regulation of MEK/ERK/p90RSK Signaling Cascade in Brain Ischemic Injury
- SUNG Jin-Hee,KIM Myeong-Ok,KOH Phil-Ok
- Journal of Veterinary Medical Science advpub(0), 1108250617, 2011
- … This study investigated whether nicotinamide exerts a neuroprotective effect through the activation of Raf-mitogen-activated protein kinase kinase (MEK)-ERK and its downstream targets, including p90 ribosomal S6 kinase (p90RSK) and Bad. … As part of the downstream cascade, nicotinamide inhibits the injury-induced decrease in p90RSK and Bad phosphorylation. …
- NAID 130001032922
- Melatonin Attenuates the Cerebral Ischemic Injury via the MEK/ERK/p90RSK/Bad Signaling Cascade(Anatomy)
- KOH Phil-Ok
- The journal of veterinary medical science 70(11), 1219-1223, 2008-11-25
- … This study investigated whether melatonin inhibits the apoptotic signal through the activation of Raf-MEK-ERK and its downstream targets, including 90 ribosomal S6 kinase (p90RSK) and Bad. … Also, it inhibits the injury-induced decrease of p90RSK and Bad phosphorylation. …
- NAID 110006987058
Related Links
- 1. Mol Cell Biol. 2003 Jul;23(14):4796-804. Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity. Roux PP(1), Richards SA, Blenis J. Author ...
- Stimulation of the Ras/extracellular signal-regulated kinase (ERK) pathway can modulate cell growth, proliferation, survival, and motility. The p90 ribosomal S6 kinases (RSKs) comprise a family of serine/threonine kinases ...
Related Pictures
★リンクテーブル★
| リンク元 | 「ERK」「90-kDa ribosomal protein S6 kinase」「p90リボソームS6キナーゼ」「p90 RSK」 |
| 関連記事 | 「S6」「kinase」「ribosomal」「S6 kinase」「S」 |
「ERK」
- 同
- [[]] extracellular-signal-regulated kinase
- 関
- MAPキナーゼスーパーファミリーカスケード
- MAPKファミリーに含まれるERKファミリーを構成
- キナーゼサブドメインVIIIの活性化ループに存在するリン酸化部位の配列がTEY
- セリンスレオニンキナーゼ
- MAPKKであるMEK1,MEK2によってスレオニンとチロシン残基がリン酸化され、活性化される。
- ERK1/2の基質
- 転写因子：Elk-1, Ets1, Sapla, STAT
- キナーゼ：p90rsk(p90 ribosomal S6 kinase), MNK1/MNK2
- cPLA2
- EGF受容体
- Sos
- 細胞骨格構成タンパク質(Map2, Tau)
- 同
- extracellular-signal-regulated kinase
「90-kDa ribosomal protein S6 kinase」
- MAPキナーゼで活性化される細胞内シグナリング酵素
- 関
- p90 ribosomal S6 kinase
「p90リボソームS6キナーゼ」
「p90 RSK」
「S6」
- 関
- 肺区域
- 肺区域の一つ。下葉に属する。背側の中等度高位を占める。上-下葉区。S6に向かう気管支は前後軸に沿って背側に向かうため、胸部単純X線写真上 ○ が見える。
「kinase」
[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase
「ribosomal」
- リボソームの、リボソーム性の
「S6 kinase」
「S」