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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/11/26 21:34:14」(JST)

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Oxaceprol is an anti-inflammatory drug used in the treatment of osteoarthritis.^[1] It is derived from L-proline, a DNA-encoded amino acid. The active effect of Oxaceprol is to inhibit the adhesion and migration of white blood cells.^[2]

References[edit]

^ Herrmann G, Steeger D, Klasser M et al. (2000). "Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac". Clin. Rheumatol. 19 (2): 99–104. doi:10.1007/s100670050025. PMID 10791619.
^ Clayton, James J. (August 2007), "Nutraceuticals in the Management of Osteoarthritis", Orthopedics 30 (8), retrieved 2013-06-08.

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English Journal

A comparison of the therapeutic efficacy of diclofenac in osteoarthritis: a systematic review of randomised controlled trials.

Pavelka K.SourceInstitute of Rheumatology and Clinic of Rheumatology, Charles University, Prague, Czech Republic. pavelka@revma.cz
Current medical research and opinion.Curr Med Res Opin.2012 Jan;28(1):163-78.
OBJECTIVE: Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) commonly prescribed for pain relief in osteoarthritis (OA). The relative efficacy of diclofenac compared to other pain relief medications used in OA (e.g., alternative NSAIDs, cyclooxygenase type 2 [COX-2] inhibitors) is uncertai
PMID 22168216

Determination of oxaceprol in rat plasma by LC-MS/MS and its application in a pharmacokinetic study.

Gu J, Chen N, Ding G, Zhang Z.SourceDepartment of Pharmacy, Eye & ENT Hospital of Fudan University, Shanghai 200031, China. gujifeng1949@126.com
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2011 Jan 5;54(1):173-8. Epub 2010 Aug 19.
A sensitive method for the quantification of oxaceprol in rat plasma using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed. Sample pretreatment involved a simple protein precipitation by the addition of 60 μL of acetonitrile-methanol (1:2, v/v) to 20 μL pla
PMID 20832228

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「AHP」

Oxaceprol
Systematic (IUPAC) name
	(4R)-1-acetyl-4-hydroxy-L-proline
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	33996-33-7
ATC code	D11AX09 M01AX24
PubChem	CID 65784
UNII	Q0XV76B96L
KEGG	D07215
Synonyms	(2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid
Chemical data
Formula	C7H11NO4
Mol. mass	172.159 g/mol
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関: afterhyperpolarization、oxaceprol

[pmid10791619-1] Herrmann G, Steeger D, Klasser M et al. (2000). "Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac". Clin. Rheumatol. 19 (2): 99–104. doi:10.1007/s100670050025. PMID 10791619.

[Clayton2007-2] Clayton, James J. (August 2007), "Nutraceuticals in the Management of Osteoarthritis", Orthopedics 30 (8), retrieved 2013-06-08.

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oxaceprol