organomercurial poisoning

WordNet

the physiological state produced by a poison or other toxic substance (同)toxic condition, intoxication
the act of giving poison to a person or animal with the intent to kill

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A brain proteome profile in rats exposed to methylmercury or thimerosal (ethylmercury).

de Oliveira Souza VC1, de Marco KC1, Laure HJ2, Rosa JC2, Barbosa F Jr1.
Journal of toxicology and environmental health. Part A.J Toxicol Environ Health A.2016;79(12):502-12. doi: 10.1080/15287394.2016.1182003.
Exposure to organomercurials has been associated with harmful effects on the central nervous system (CNS). However, the mechanisms underlying organomercurial-mediated neurotoxic effects need to be elucidated. Exposure to toxic elements may promote cellular modifications such as alterations in protei
PMID 27294299

Geier DA1, King PG2, Hooker BS3, Dórea JG4, Kern JK5, Sykes LK6, Geier MR7.
Clinica chimica acta; international journal of clinical chemistry.Clin Chim Acta.2015 Apr 15;444:212-20. doi: 10.1016/j.cca.2015.02.030. Epub 2015 Feb 21.
INTRODUCTION: Thimerosal (or Thiomersal) is a trade name for an organomercurial compound (sodium ethyl-mercury (Hg) thiosalicylate) that is 49.55% Hg by weight, which rapidly decomposes in aqueous saline solutions into ethyl-Hg hydroxide and ethyl-Hg chloride. Developed in 1927, it has been and is s
PMID 25708367

ITPKC susceptibility in Kawasaki syndrome as a sensitizing factor for autoimmunity and coronary arterial wall relaxation induced by thimerosal's effects on calcium signaling via IP3.

Yeter D1, Deth R.
Autoimmunity reviews.Autoimmun Rev.2012 Oct;11(12):903-8. doi: 10.1016/j.autrev.2012.03.006. Epub 2012 Apr 1.
Recently, a single nucleotide polymorphism (SNP) of the inositol 1,4,5-triphosphate kinase C (ITPKC), rs28493229, was found to passively confer susceptibility for Kawasaki syndrome (KS) and subsequent coronary arterial lesions. This association is believed to be the result of defective phosphorylati
PMID 22498790