opsonophagocytosis

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1. 糖尿病患者の易感染性 susceptibility to infections in persons with diabetes mellitus
2. 基礎疾患の状態、環境曝露、およびその他の原因による二次性免疫不全症 secondary immunodeficiency due to underlying disease states environmental exposures and miscellaneous causes
3. 髄膜炎菌感染の疫学 epidemiology of neisseria meningitidis infection
4. マンノース結合レクチン欠損症 mannose binding lectin deficiency

Scorza M1, Liguori R1, Elce A2, Salvatore F1, Castaldo G3.
Clinica chimica acta; international journal of clinical chemistry.Clin Chim Acta.2015 Dec 7;451(Pt A):78-81. doi: 10.1016/j.cca.2015.03.007. Epub 2015 Mar 14.
Mannose binding lectin (MBL) is a protein of innate immunity that activates the complement and promotes opsonophagocytosis. The deficiency of MBL due to several common gene polymorphisms significantly enhances the risk of severe infections, particularly in the neonatal age and in childhood. On the c
PMID 25783214

Surface Glycopolymers Are Crucial for In Vitro Anti-Wall Teichoic Acid IgG-Mediated Complement Activation and Opsonophagocytosis of Staphylococcus aureus.

Lee JH1, Kim NH1, Winstel V2, Kurokawa K3, Larsen J4, An JH1, Khan A1, Seong MY1, Lee MJ1, Andersen PS4, Peschel A2, Lee BL5.
Infection and immunity.Infect Immun.2015 Nov;83(11):4247-55. doi: 10.1128/IAI.00767-15. Epub 2015 Aug 17.
The cell envelopes of many Gram-positive bacteria contain wall teichoic acids (WTAs). Staphylococcus aureus WTAs are composed of ribitol phosphate (RboP) or glycerol phosphate (GroP) backbones substituted with d-alanine and N-acetyl-d-glucosamine (GlcNAc) or N-acetyl-d-galactosamine (GalNAc). Two WT
PMID 26283333

Identification of the Streptococcus pyogenes surface antigens recognised by pooled human immunoglobulin.

Reglinski M1, Gierula M1, Lynskey NN1, Edwards RJ1, Sriskandan S1.
Scientific reports.Sci Rep.2015 Oct 28;5:15825. doi: 10.1038/srep15825.
Immunity to common bacteria requires the generation of antibodies that promote opsonophagocytosis and neutralise toxins. Pooled human immunoglobulin is widely advocated as an adjunctive treatment for clinical Streptococcus pyogenes infection however, the protein targets of the reagent remain ill def
PMID 26508447

B1b lymphocyte-derived antibodies control Borrelia hermsii independent of Fcα/μ receptor and in the absence of host cell contact

Colombo Matthew J.,Abraham David,Shibuya Akira,Alugupalli Kishore R.
Immunologic research 51(2-3), 249-256, 2011-12
… hermsii does not require opsonophagocytosis and indicate that a mechanism for in vivo B1b cell-mediated protection is through the generation of bactericidal IgM. …
NAID 120003752225

EndoS and SpeB from Streptococcus pyogenes inhibit immunoglobulin-mediated opsonophagocytosis

Mannose-binding lectin : targeting the microbial world for complement attack and opsonophagocytosis