癌胎児性フィブロネクチン
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English Journal
- EDB Fibronectin Specific Peptide for Prostate Cancer Targeting.
- Han Z1,2, Zhou Z1,2, Shi X1,2, Wang J1,2, Wu X1,2, Sun D1,2, Chen Y1,2, Zhu H1,2, Magi-Galluzzi C1,2, Lu ZR1,2.
- Bioconjugate chemistry.Bioconjug Chem.2015 May 20;26(5):830-8. doi: 10.1021/acs.bioconjchem.5b00178. Epub 2015 Apr 15.
- Extradomain-B fibronectin (EDB-FN), one of the oncofetal fibronectin (onfFN) isoforms, is a high-molecular-weight glycoprotein that mediates cell adhesion and migration. The expression of EDB-FN is associated with a number of cancer-related biological processes such as tumorigenesis, angiogenesis, a
- PMID 25848940
- Tenascin-C and carcinoma cell invasion in oral and urinary bladder cancer.
- Berndt A1, Richter P, Kosmehl H, Franz M.
- Cell adhesion & migration.Cell Adh Migr.2015;9(1-2):105-11. doi: 10.1080/19336918.2015.1005463.
- Carcinoma invasion is a complex process regulated by genetic and epigenetic factors as well. A relevant supportive condition for cancer cell migration is the reorganization of the extracellular matrix (ECM), which is realized in an orchestrated multicellular manner including carcinoma cells and stro
- PMID 25793577
- Evaluation of antibody-chemokine fusion proteins for tumor-targeting applications.
- Hess C1, Neri D2.
- Experimental biology and medicine (Maywood, N.J.).Exp Biol Med (Maywood).2014 May 28;239(7):842-852. [Epub ahead of print]
- There is an increasing biotechnological interest in the 'arming' of therapeutic antibodies with bioactive payloads. While many antibody-cytokine fusion proteins have been extensively investigated in preclinical and clinical studies, there are only few reports related to antibody-chemokine fusion pro
- PMID 24872435
Japanese Journal
- (2)周産期科サイドよりみた浸潤子宮頸癌に対する妊孕性温存療法の現状と課題(<特集>第62回学術講演会 シンポジウム1 婦人科癌における妊孕性温存治療(手術および薬物療法))
- 石岡 伸一
- 日本産科婦人科學會雜誌 62(10), 2096-2106, 2010-10-01
- … Originally, we started anti-infectious treatments after the detection of infectious signs such as the elevation of granulocyte elastase level and oncofetal fibronectin level, or the positive vaginal flora. … Furthermore we carefully checked vaginal flora, the granulocyte elastase level, and the oncofetal fibronectin level in vaginal secretion, as well as the cervical length and abdominal tension of patients in shorter interval than usual patients with preterm labor. …
- NAID 110007730376
- 臍帯静脈血管内皮細胞における高濃度ブドウ糖によって惹起されるTGF-β1と癌胎児性ファイブロネクチンの増加に対する 2-Aminophenoxazine-3-one の作用
- 清水 彩子,福田 元
- 東京醫科大學雜誌 = THE JOURNAL OF TOKYO MEDICAL UNIVERSITY 65(2), 106-111, 2007-03-25
- NAID 10020170524
- 平野 仁嗣,山崎 峰夫,原田 直哉 [他],森川 肇
- 産婦人科の進歩 57(1), 1-12, 2005
- 早産の原因の1つに絨毛羊膜炎が挙げられるが,子宮頸管から絨毛膜や羊膜の組織に炎症が発生すると,局所で産生された生理活性物質によって子宮収縮や子宮頸管熟化が促され,早産に至ると考えられる.実地臨床では,全身の炎症マーカーや腟から子宮頸管の局所的マーカーが診断のために用いられてはいるが,false positiveやfalse negativeが少なくない.そこで,切迫早産妊婦において腟内の微生物学 …
- NAID 130001223330
Related Links
- 1. Invest Ophthalmol Vis Sci. 2004 Jan;45(1):287-95. Oncofetal fibronectin in diabetic retinopathy. Khan ZA, Cukiernik M, Gonder JR, Chakrabarti S. Department of Pathology, University of Western Ontario, London, Ontario, Canada. ...
- Epithelial-mesenchymal transition (EMT) has been shown to play a key role in embryogenesis and cancer progression. We previously found that fibronectin (FN) carrying O-GalNAc at a specific site is selectively expressed in cancer ...
★リンクテーブル★
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- 英
- oncofetal fibronectin
- 細胞外マトリックス蛋白質の一頭
- 頚管粘液中や膣分泌物中には通常認められない
- 卵膜の損傷や脆弱化、子宮収縮などで絨毛膜が損傷されると、癌胎児性フィブロネクチンが頚管内、腟内に流出する
- 早産発生の1-2週間前より高値
- 20周以前では生理的に高値、24週以降に用いられる。
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- 関
- carcinoembryonic