WordNet

the ending of a series or sequence; "the Alpha and the Omega, the first and the last, the beginning and the end"--Revelation (同)Z
the last (24th) letter of the Greek alphabet

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Interactions between calcium channels and SK channels in midbrain dopamine neurons and their impact on pacemaker regularity: contrasting roles of N- and l-type channels.

de Vrind V1, Scuvée-Moreau J2, Drion G3, Hmaied C2, Philippart F2, Engel D2, Seutin V4.
European journal of pharmacology.Eur J Pharmacol.2016 Jun 27. pii: S0014-2999(16)30405-8. doi: 10.1016/j.ejphar.2016.06.046. [Epub ahead of print]
Although small-conductance Ca2+-activated K+ (SK) channels and various types of voltage-gated Ca2+ (Cav) channels have been described in midbrain dopaminergic neurons, the nature of their interactions is unclear. More particularly, the role of various Cav channel types in either promoting irregulari
PMID 27364758

Sodium-calcium exchanger and R-type Ca(2+) channels mediate spontaneous [Ca(2+)]i oscillations in magnocellular neurones of the rat supraoptic nucleus.

Kortus S1, Srinivasan C2, Forostyak O3, Zapotocky M4, Ueta Y5, Sykova E6, Chvatal A7, Verkhratsky A8, Dayanithi G9.
Cell calcium.Cell Calcium.2016 Jun;59(6):289-98. doi: 10.1016/j.ceca.2016.03.010. Epub 2016 Mar 31.
Isolated supraoptic neurones generate spontaneous [Ca(2+)]i oscillations in isolated conditions. Here we report in depth analysis of the contribution of plasmalemmal ion channels (Ca(2+), Na(+)), Na(+)/Ca(2+) exchanger (NCX), intracellular Ca(2+) release channels (InsP3Rs and RyRs), Ca(2+) storage o
PMID 27052156

Central Nervous System-Toxic Lidocaine Concentrations Unmask L-Type Ca2+ Current-Mediated Action Potentials in Rat Thalamocortical Neurons: An In Vitro Mechanism of Action Study.

Putrenko I1, Ghavanini AA, Meyer Schöniger KS, Schwarz SK.
Anesthesia and analgesia.Anesth Analg.2016 May;122(5):1360-9. doi: 10.1213/ANE.0000000000001158.
BACKGROUND: High systemic lidocaine concentrations exert well-known toxic effects on the central nervous system (CNS), including seizures, coma, and death. The underlying mechanisms are still largely obscure, and the actions of lidocaine on supraspinal neurons have received comparatively little stud
PMID 26771269

A Negative Inotropic Effect of Omega-Conotoxin GVIA in Isolated, Blood-Perfused Dog Right Atria.

Ren Lei-Ming,Furukawa Yasuyuki,Karasawa Yasuyuki,Murakami Makoto,Takayama Shin,Inoue Yasurou,Sawaki Shoji,Chiba Shigetoshi
The Japanese Journal of Pharmacology 57(4), 613-616, 1991
… Using an isolated, blood-perfused canine atrial preparation, we investigated the effects of omega-conotoxin GVIA (omega-CgTX), a blocker of N-type voltage-operated calcium channels, on the atrial contractile force and sinus rate. …
NAID 130000833282