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Exophthalmos | |
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Classification and external resources | |
Patient with left eye proptosis
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ICD-10 | H05.2 |
ICD-9 | 376.2-376.3 |
DiseasesDB | 18612 |
MedlinePlus | 003033 |
eMedicine | oph/616 |
MeSH | D005094 |
Exophthalmos, also called exophthalmia or proptosis, is a bulging of the eye anteriorly out of the orbit. Exophthalmos can be either bilateral (as is often seen in Graves' disease) or unilateral (as is often seen in an orbital tumor). Complete or partial dislocation from the orbit is also possible from trauma or swelling of surrounding tissue resulting from trauma.
In the case of Graves' disease, the displacement of the eye is due to abnormal connective tissue deposition in the orbit and extraocular muscles which can be visualized by CT or MRI.[1]
If left untreated, exophthalmos can cause the eyelids to fail to close during sleep leading to corneal dryness and damage. Another possible complication would be a form of redness or irritation called "Superior limbic keratoconjunctivitis", where the area above the cornea becomes inflamed as a result of increased friction when blinking. The process that is causing the displacement of the eye may also compress the optic nerve or ophthalmic artery, leading to blindness.
Measurement of the degree of exophthalmos is performed using an exophthalmometer.
Most sources define exophthalmos/proptosis as a protrusion of the globe greater than 18 mm.[1]
The term exophthalmos is often used when describing proptosis associated with Graves' disease.[2]
Proptosis is the anterior displacement of the eye from the orbit. Since the orbit is closed off posteriorly, medially and laterally, any enlargement of structures located within will cause the anterior displacement of the eye.[3] Swelling or enlargement of the lacrimal gland causes inferior medial and anterior dislocation of the eye. This is because the lacrimal glands are located superiorly and laterally in the orbit.[3]
Inflammatory/Infection:
Neoplastic:
Cystic:
Vascular:
Others:
Exophthalmos is commonly found in dogs. It is seen in brachycephalic (short nosed) dog breeds because of the shallow orbit. However, it can lead to keratitis secondary to exposure of the cornea. Exophthalmos is commonly seen in the Pug, Boston Terrier, Pekingese, and Shih Tzu.
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リンク元 | 「眼球突出」「眼球前出」 |
関連記事 | 「ocular」「proptosis」 |
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