WordNet

consolidating two or more things; union in (or into) one body
including by incorporating
a phosphoric ester of a nucleoside; the basic structural unit of nucleic acids (DNA or RNA) (同)base

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1. 遺伝性疾患の基本原則 basic principles of genetic disease
2. 小児における急性リンパ芽球性白血病の治療の概要 overview of the treatment of acute lymphoblastic leukemia in children
3. 鎌状細胞貧血における臨床的ばらつき clinical variability in sickle cell anemia
4. 前立腺癌の危険因子 risk factors for prostate cancer
5. 遺伝的変異の概要 overview of genetic variation

Cytochrome P450 CYP3A in marsupials: Cloning and characterisation of the second identified CYP3A subfamily member, isoform 3A78 from koala (Phascolarctos cinereus).

El-Merhibi A, Ngo SN, Crittenden TA, Marchant CL, Stupans I, McKinnon RA.SourceWomen's and Children's Health Research Institute, Women's and Children's Hospital, North Adelaide, SA 5006, Australia.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.Comp Biochem Physiol C Toxicol Pharmacol.2011 Nov;154(4):367-76. Epub 2011 Jul 23.
Cytochromes P450 (CYPs) are critically important in the oxidative metabolism of a diverse array of xenobiotics and endogenous substrates. Previously, we cloned and characterised the CYP2C, CYP4A, and CYP4B gene subfamilies from marsupials and demonstrated important species-differences in both activi
PMID 21807118

Computational analysis of the transcriptional regulation of the adenine nucleotide translocator isoform 4 gene and its role in spermatozoid glycolytic metabolism.

Dupont PY, Stepien G.AbstractComputational phylogenetic analysis coupled to promoter sequence alignment was used to understand mechanisms of transcriptional regulation and to identify potentially coregulated genes. Our strategy was validated on the human ANT4 gene which encodes the fourth isoform of the mitochondrial adenine nucleotide translocator specifically expressed during spermatogenesis. The movement of sperm flagella is driven mainly by ATP generated by glycolytic pathways, and the specific induction of the mitochondrial ANT4 protein presented an interesting puzzle. We analysed the sequences of the promoters, introns and exons of 30 mammalian ANT4 genes and constructed regulatory models. The whole human genome and promoter database were screened for genes that were potentially regulated by the generated models. 80% of the identified co-regulated genes encoded proteins with specific roles in spermatogenesis and with functions linked to male reproduction. Our in silico study enabled us to precise the specific role of the ANT4 isoform in spermatozoid bioenergetics.
Gene.Gene.2011 Nov 1;487(1):38-45. Epub 2011 Jul 31.
Computational phylogenetic analysis coupled to promoter sequence alignment was used to understand mechanisms of transcriptional regulation and to identify potentially coregulated genes. Our strategy was validated on the human ANT4 gene which encodes the fourth isoform of the mitochondrial adenine nu
PMID 21827840

A semi-automated non-radioactive system for measuring recovery of RNA synthesis and unscheduled DNA synthesis using ethynyluracil derivatives.

Nakazawa Yuka,Yamashita Shunichi,Lehmann Alan R,Ogi Tomoo
DNA repair 9(5), 506-516, 2010-05-04
… Nucleotide excision repair (NER) removes the major UV-photolesions from cellular DNA. … Until very recently, reliable methods for these assays involved measurements of incorporation of radio-labeled nucleosides. … We have established non-radioactive procedures for determining UDS and RRS levels by incorporation of recently developed alkyne-conjugated nucleoside analogues, 5-ethynyl-2'-deoxyuridine (EdU) and 5-ethynyuridine (EU). …
NAID 120001945561

The impact of the overexpression of human UDP-galactose transporter gene hUGT1 in tobacco plants(PLANT BIOTECHNOLOGY)

Mohamed Khalil Mohamed Farouk,Kajiura Hiroyuki,Fujiyama Kazuhito,Koike Kanae,Ishida Nobuhiro,Tanaka Nobukazu
Journal of bioscience and bioengineering 109(2), 159-169, 2010-02
… These results suggested that because of higher UDP-galactose transport from the cytosol to the Golgi apparatus, galactose incorporation into polysaccharide side chains of AGP is involved in the gibberellin response, resulting in morphological and architectural changes. …
NAID 110007573247