Cytoplasmic polyadenylation element-binding protein (CPEB)3 is a nucleocytoplasm-shuttling RNA-binding protein and predominantly resides in the cytoplasm where it represses target RNA translation. When translocated into the nucleus, CPEB3 binds to Stat5b and downregulates Stat5b-dependent transcript
Kim EJ.SourceDepartment of Science Education-Chemistry Major, Daegu University, Gyeongbuk 712-714, Korea. eunkim@daegu.ac.kr
Molecules (Basel, Switzerland).Molecules.2011 Feb 28;16(3):1987-2022. doi: 10.3390/molecules16031987.
The concepts of both protein glycosylation and cellular signaling have been influenced by O-linked-β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation) on the hydroxyl group of serine or threonine residues. Unlike conventional protein glycosylation, O-GlcNAcylation is localized in the nu
Evolution of the Archaea: emerging views on origins and phylogeny.
Fournier GP, Dick AA, Williams D, Gogarten JP.SourceDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. g4nier@mit.edu
Research in microbiology.Res Microbiol.2011 Jan;162(1):92-8. doi: 10.1016/j.resmic.2010.09.016. Epub 2010 Oct 27.
Of the three domains of life, the Archaea are the most recently discovered and, from the perspective of systematics, perhaps the least understood. More than three decades after their discovery, there is still no overwhelming consensus as to their phylogenetic status, with diverse evidence supporting
P68 RNA helicase is a prototypical DEAD box RNA helicase. The protein plays a very important role in early organ development and maturation. In consistence with the function of the protein in transcriptional regulation and pre-mRNA ...