関: norfenefrine hydrochloride

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/10/01 23:07:32」(JST)

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Norfenefrine (INN; brand names Coritat, Energona, Hypolind, and Novadral), also known as m-octopamine (or 3-octopamine) and 3,β-dihydroxyphenethylamine, is an adrenergic agent used as a sympathomimetic drug which is marketed in Europe, Japan, and Mexico.^[1]^[2] Along with its structural isomer p-octopamine and the tyramines, norfenefrine is a naturally occurring, endogenous trace amine and plays a role as a minor neurotransmitter in the brain.^[3]

References

^ F.. Macdonald (1997). = DeX7jgInYFMC&pg = PA104 Dictionary of Pharmacological Agents. CRC Press. p. 104. ISBN 978-0-412-46630-4. http://books.google.com/books?id = DeX7jgInYFMC&pg = PA104. Retrieved 24 April 2012.
^ = 5GpcTQD_L2oC&pg = PA750 Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 750. ISBN 978-3-88763-075-1. http://books.google.com/books?id = 5GpcTQD_L2oC&pg = PA750. Retrieved 24 April 2012.
^ Danielson TJ, Boulton AA, Robertson HA (December 1977). "m-Octopamine, p-octopamine and phenylethanolamine in rat brain: a sensitive, specific assay and the effects of some drugs". Journal of Neurochemistry 29 (6): 1131–5. PMID 340613.

English Journal

A multichannel electrophoresis microchip platform for rapid chiral selector screening.

Gao Y, Luo Y, Qin J, Lin B.SourceDalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, P. R. China.
Electrophoresis.Electrophoresis.2008 May;29(9):1918-23.
This study presents a four-channel electrophoresis chip platform, featuring double-cross hydrostatic sample injection, for rapid chiral selector screening. This platform needs only five electrodes to drive microchip electrophoresis in four separate channels for screening four chiral selectors at a t
PMID 18384040

A new copper(I)-tetrahydrosalen-catalyzed asymmetric Henry reaction and its extension to the synthesis of (S)-norphenylephrine.

Xiong Y, Wang F, Huang X, Wen Y, Feng X.SourceKey Laboratory of Green Chemistry and Technology (Sichuan University), Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China.
Chemistry (Weinheim an der Bergstrasse, Germany).Chemistry.2007;13(3):829-33.
A new chiral hydrogenated salen catalyst has been developed for the asymmetric Henry reaction which produces the expected products in moderate to high yields (up to 98 %) with excellent enantioselectivities (up to 96 % ee). A variety of aromatic, heteroaromatic, enal, and aliphatic aldehydes were fo
PMID 17068834

Japanese Journal

心筋障害と血中酸素分圧との関連におけるSympathomimetic Aminesの作用

沢辺隆司,府川和永,佐藤進
藥學雜誌 101(2), 161-168, 1981-02-25
… The decrease in Po_2 due to dl-norfenefrine, which causes very little cardiac lesion and acts on the α-receptor, was not significant. …
NAID 110003650127

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Norfenefrine
Systematic (IUPAC) name
	3-(2-amino-1-hydroxyethyl)phenol
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	℞ Prescription only
Identifiers
CAS number	536-21-0 ; 15308-34-6 (hydrochloride)
ATC code	C01CA05
PubChem	CID 4538
ChemSpider	4379
UNII	D2P3M6SRN5
KEGG	D08286
ChEMBL	CHEMBL358040
Synonyms	Norfenephrine; Norphenephrine; Norphenylephrine; meta-Norsynephrine; meta-Octopamine; 3-Octopamine
Chemical data
Formula	C8H11NO2
Mol. mass	153.178 g/mol
	SMILES OC(c1cc(O)ccc1)CN;
	InChI InChI=1S/C8H11NO2/c9-5-8(11)6-2-1-3-7(10)4-6/h1-4,8,10-11H,5,9H2 ; Key:LRCXRAABFLIVAI-UHFFFAOYSA-N ;
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