非細菌性血栓性心内膜炎
WordNet
- inflammation of the endocardium and heart valves
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/04/04 14:10:20」(JST)
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| Nonbacterial thrombotic endocarditis |
| Classification and external resources |
| DiseasesDB |
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Non-bacterial thrombotic endocarditis (NBTE) is a form of endocarditis in which small sterile vegetations are deposited on the valve leaflets. Formerly known as marantic endocarditis, which comes from the Greek marantikos, meaning “wasting away.”[1] The term "marantic endocarditis" is still sometimes used to emphasize the association with a wasting state[2] such as cancer.[3]
Contents
- 1 Histopathology
- 2 Risk factors
- 3 Valve predilection
- 4 Diagnosis
- 5 References
Histopathology
Grossly, vegetations form along lines of valve closure and are generally symmetric with a smooth or verrucoid (warty) texture. Histologically, lesions are composed of fibrin[4] (eosinophilic) and platelets but, unlike bacterial etiologies, contain little evidence of PMNs, microorganisms or inflammation.
Risk factors
Marantic vegetations are often associated with previous rheumatic fever.
Other risk factors include:
- hypercoagulable states
- malignant cancers, especially mucin-producing adenocarcinomas (most commonly associated with pancreatic adenocarcinomas)
- systemic lupus erythematosus: Referred to as Libman-Sacks endocarditis
- trauma (e.g., catheters)
Valve predilection
The disease affects the valves with the following predilection:
aortic valve > mitral valve > tricuspid valve > pulmonary valve [5]
Diagnosis
Due to the non-invasive nature of NBTE, clinical examination may or may not reveal a new murmur.
An embolic stroke may be the first feature to suggest the diagnosis of NBTE. An echocardiograph may be used to further assess for valvular lesions.
References
- ^ Neurological Sequelae of Infectious Endocarditis at eMedicine
- ^ "Noninfective Endocarditis: Endocarditis: Merck Manual Professional". Retrieved 2008-12-22.
- ^ "Definition: marantic endocarditis from Online Medical Dictionary". Retrieved 2008-12-22.
- ^ "nonbacterial thrombotic endocarditis" at Dorland's Medical Dictionary
- ^ Eiken PW, Edwards WD, Tazelaar HD, McBane RD, Zehr KJ (2001). "Surgical pathology of nonbacterial thrombotic endocarditis in 30 patients, 1985–2000". Mayo Clin. Proc. 76 (12): 1204–12. doi:10.4065/76.12.1204. PMID 11761501.
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Cardiovascular disease I00–I52, 390–429
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| Ischaemic |
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Coronary disease
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- Coronary artery disease (CAD)
- Coronary artery aneurysm
- Coronary artery dissection
- Coronary thrombosis
- Coronary vasospasm
- Myocardial bridge
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Active ischemia
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- Angina pectoris
- Prinzmetal's angina
- Stable angina
- Acute coronary syndrome
- Myocardial infarction
- Unstable angina
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Sequelae
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- hours
- Hibernating myocardium
- Myocardial stunning
- days
- weeks
- Aneurysm of heart / Ventricular aneurysm
- Dressler syndrome
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| Layers |
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Pericardium
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- Pericarditis
- Acute
- Chronic / Constrictive
- Pericardial effusion
- Cardiac tamponade
- Hemopericardium
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Myocardium
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- Myocarditis
- Cardiomyopathy: Dilated (Alcoholic), Hypertrophic, and Restrictive
- Loeffler endocarditis
- Cardiac amyloidosis
- Endocardial fibroelastosis
- Arrhythmogenic right ventricular dysplasia
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Endocardium /
valves
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Endocarditis
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- infective endocarditis
- Subacute bacterial endocarditis
- non-infective endocarditis
- Libman–Sacks endocarditis
- Nonbacterial thrombotic endocarditis
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Valves
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- mitral
- regurgitation
- prolapse
- stenosis
- aortic
- tricuspid
- pulmonary
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Conduction /
arrhythmia |
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Bradycardia
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- Sinus bradycardia
- Sick sinus syndrome
- Heart block: Sinoatrial
- AV
- Intraventricular
- Bundle branch block
- Right
- Left
- Left anterior fascicle
- Left posterior fascicle
- Bifascicular
- Trifascicular
- Adams–Stokes syndrome
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Tachycardia
(paroxysmal and sinus)
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Supraventricular
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- Atrial
- Junctional
- AV nodal reentrant
- Junctional ectopic
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Ventricular
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- Accelerated idioventricular rhythm
- Catecholaminergic polymorphic
- Torsades de pointes
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Premature contraction
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- Atrial
- Junctional
- Ventricular
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Pre-excitation syndrome
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- Lown–Ganong–Levine
- Wolff–Parkinson–White
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Flutter / fibrillation
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- Atrial flutter
- Ventricular flutter
- Atrial fibrillation
- Ventricular fibrillation
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Pacemaker
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- Ectopic pacemaker / Ectopic beat
- Multifocal atrial tachycardia
- Pacemaker syndrome
- Parasystole
- Wandering pacemaker
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Long QT syndrome
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- Andersen–Tawil
- Jervell and Lange-Nielsen
- Romano–Ward
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Cardiac arrest
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- Sudden cardiac death
- Asystole
- Pulseless electrical activity
- Sinoatrial arrest
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Other / ungrouped
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- hexaxial reference system
- Right axis deviation
- Left axis deviation
- QT
- T
- ST
- Osborn wave
- ST elevation
- ST depression
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| Cardiomegaly |
- Ventricular hypertrophy
- Left
- Right / Cor pulmonale
- Atrial enlargement
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| Other |
- Cardiac fibrosis
- Heart failure
- Diastolic heart failure
- Cardiac asthma
- Rheumatic fever
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UpToDate Contents
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English Journal
- Koolaee RM, Moran AA, Shahane A.
- Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases.J Clin Rheumatol.2013 Aug;19(5):301. doi: 10.1097/RHU.0b013e31829d5cd7.
- PMID 23884192
- Comment on diffuse alveolar hemorrhage and Libman-Sacks endocarditis as a manifestation of possible primary antiphospholipid syndrome.
- Lederer W, Wiedermann FJ.
- Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases.J Clin Rheumatol.2013 Aug;19(5):300. doi: 10.1097/RHU.0b013e31829d5dd2.
- PMID 23884191
- Antiphospholipid syndrome and recurrent thrombotic valve disease.
- Scantlebury DC, Nkomo VT, Enriquez-Sarano M.
- Journal of the American College of Cardiology.J Am Coll Cardiol.2013 Jun 11;61(23):e177. doi: 10.1016/j.jacc.2012.12.058.
- PMID 23743123
Japanese Journal
- Acute Myocardial Infarction Associated with Small-size Lung Cancer in a Young Woman
- Mizumura Kenji,Sugane Toshio,Ozaki Shunsuke,Ohta Hiroshi,Kouzu Yutaka,Sekiyama Akiko,Hiranuma Hisato,Terakado Masahiro,Sato Maki,Shimizu Tetsuo,Kobayashi Tomoko,Takahashi Noriaki,Hashimoto Shu
- Internal Medicine 50(18), 1997-2002, 2011
- A 34-year-old woman visited our hospital with chest pain and was diagnosed with acute myocardial infarction (AMI) on admission. Echocardiography imaging revealed the presence of complex masses in the …
- NAID 130000969311
- Nonbacterial thrombotic endocarditis complicated with stage la ovarian cancer
- TANAKA Hirohiko,ITO Masako,YOSHIDA Kayo,ASAKURA Tetsuo,TANIGUCHI Haruki
- International journal of clinical oncology : official journal of the Japan Society of Clinical Oncology 14(4), 369-371, 2009-08-01
- NAID 10025864279
Related Links
- nonbacterial thrombotic endocarditis [-baktir′ē·əl] Etymology: L, non + bakerion, small rod one of the three main types of endocarditis, characterized by various kinds of lesions affecting the heart valves, most often on the left side of ...
- Nonbacterial thrombotic endocarditis (NBTE) is a rare condition that refers to a spectrum of noninfectious lesions of the heart valves that is most commonly seen in advanced malignancy. NBTE is often an autopsy finding. However ...
Related Pictures
★リンクテーブル★
[★]
- 英
- nonbacterial thrombotic endocarditis NBTE, nonmycotic thrombotic endocarditis
- 同
- 疣贅性心内膜炎 vegetative endocarditis
[show details]
[★]
非細菌性血栓性心内膜炎 nonbacterial thrombotic endocarditis
[★]
- 関
- thrombus n.血栓
- thrombi n.(pl.)血栓