WordNet

the 15th letter of the Roman alphabet (同)o
the blood group whose red cells carry neither the A nor B antigens; "people with type O blood are universal donors" (同)type_O, group O

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《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
《呼び掛けの名前の前につけて》『おお』,あ / (驚き・恐れ・喜び・苦痛などを表して)『おお』,ああ,まあ / 《肯定・否定を強めて》
oxygenの化学記号
ohmオーム / Old
母斑(ぼはん)(先天性のあざ・ほくろ・そばかすなど)
OLD French古[代]フランス語

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/07/07 18:39:49」(JST)

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Nevus of Ota (also known as "congenital melanosis bulbi",^[1] "nevus fuscoceruleus ophthalmomaxillaris", "oculodermal melanocytosis",^[2]^:700 and "Oculomucodermal melanocytosis"^[1]) is a blue hyperpigmentation^[3] that occurs on the face. It was first reported by Dr. M.T. Ota of Japan in 1939.^[4]

Nevus of Ota is caused by the entrapment of melanocytes in the upper third of the dermis. It is found on the face unilaterally and involves the first two branches of the trigeminal nerve. The sclera is involved in two-thirds of cases (causing an increased risk of glaucoma). It should not be confused with Mongolian spot, which is a birthmark caused by entrapment of melanocytes in the dermis but is located in the lumbosacral region. Women are nearly five times more likely to be affected than men, and it is rare among Caucasian people.^[5] Nevus of Ota may not be congenital, and may appear during puberty.

Skin treatment

A Q-switched laser has been successfully used to treat the condition.^[6]^[7]

Eye treatment

A specific form of conjunctivoplasty may help somewhat.^{[citation needed]}

Notable cases

Actress Daniela Ruah^[5]

References

^ ^a ^b Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. 1720–22. ISBN 1-4160-2999-0.
^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
^ Chan HH, Kono T (2003). "Nevus of Ota: clinical aspects and management". Skinmed. 2 (2): 89–96; quiz 97–8. PMID 14673306. doi:10.1111/j.1540-9740.2003.01706.x.
^ "eMedicine - Nevi of Ota and Ito : Article by Harvey Lui". Retrieved 2008-03-22.
^ ^a ^b "Daniela Ruah Officially Checks In". Esquire. September 2011. Retrieved 9 June 2016.
^ Geronemus, RG (Dec 1992). "Q-switched ruby laser therapy of nevus of Ota". Archives of Dermatology. 128 (12): 1618–22. PMID 1456756. doi:10.1001/archderm.1992.04530010056008.
^ Watanabe S, Takahashi H (1994). "Treatment of nevus of Ota with the Q-switched ruby laser". N. Engl. J. Med. 331 (26): 1745–50. PMID 7984195. doi:10.1056/NEJM199412293312604.

UpToDate Contents

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1. 色素細胞性母斑（ほくろ）以外の良性色素性皮膚病変 benign pigmented skin lesions other than melanocytic nevi moles
2. 皮膚色素過剰症に対するレーザーおよび光線療法 laser and light therapy for cutaneous hyperpigmentation
3. 眼瞼の病変 eyelid lesions
4. 先天性色素性母斑および点状黒子様母斑 congenital melanocytic nevi and speckled lentiginous nevi
5. 新生児および乳児における皮膚および頭皮の良性病変 benign skin and scalp lesions in the newborn and young infant

English Journal

Microsurgical treatment of meningeal malignant melanoma accompanied by nevus of Ota: two case reports and a literature review.

Wang J, Guo ZZ, Zhang SG, Wang YJ, Wang YB, Xing DG.
Melanoma research.Melanoma Res.2013 Dec;23(6):502-4. doi: 10.1097/CMR.0000000000000026.
PMID 24162444

A new classification of nevus of Ota.

Huang WH, Wang HW, Sun QN, Jin HZ, Liu YH, Ma DL, Zuo YG, Zheng HY, Wan K, Jing Q, Zhao YL.Author information Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.AbstractBACKGROUND: The nevus of Ota, is a common benign pigmentary dermatosis, mainly involve innervation area of first and second branch of trigeminal nerve. The classification of nevus of Ota was proposed by Tanino, based on 26 cases of nevus of Ota from 1937 to 1940. Studies about its classification are rarely seen in last 70 years, while it is still practical today.
Chinese medical journal.Chin Med J (Engl).2013 Oct;126(20):3910-4.
BACKGROUND: The nevus of Ota, is a common benign pigmentary dermatosis, mainly involve innervation area of first and second branch of trigeminal nerve. The classification of nevus of Ota was proposed by Tanino, based on 26 cases of nevus of Ota from 1937 to 1940. Studies about its classification are
PMID 24157155

Malignant melanoma from a nevus of Ota in a pediatric patient with fatal outcome.

Lindsey SF, Sanchez MI, Elgart GW, Milikowski C, Civantos FJ, Goldberg J, Grichnik JM.
Journal of the American Academy of Dermatology.J Am Acad Dermatol.2013 Oct;69(4):e195-7. doi: 10.1016/j.jaad.2013.05.009.
PMID 24034399

Japanese Journal

線維柱帯切開術が有効であった色素血管母斑症を伴う発達緑内障の1例

岡安隆,松原みどり,小林かおり [他],岡田守生
あたらしい眼科 = Journal of
NAID 10031189387

前額部に生じたPrimary dermal melanomaの1例

上尾礼子,爲政大幾,田中美紀,太田馨,岡本祐之,永田基樹,藤澤琢郎,小西将矢,新田匡幸
Skin Cancer 28(2), 190-194, 2013
　65歳，女性。数十年前から存在した右眉毛上部の色素斑に1年前より皮下腫瘤が出現し，増大してきたため近医形成外科を受診した。粉瘤疑いで切除されたが，病理組織検査で悪性黒色腫と診断され，当科紹介受診となった。前医での切除標本病理組織像では，真皮から皮下にメラニン色素を有する異型細胞の増殖を認めたが，表皮内に異型メラノサイトはみられずprimary dermal melanomaと診断した。初診時には …
NAID 130003396873

太田母斑に対するβ線外面照射療法後に生じた有棘細胞癌

神谷由紀,吉池高志,山秋孝子
Skin Cancer 28(1), 89-93, 2013
80歳，女性。50年前に顔面太田母斑に対するβ線外面照射療法をうけた。その後治療部位に潰瘍を生じ，外用療法をうけたが軽快せず，腫瘤も生じ徐々に増大したため当科初診となった。初診時，左顔面は慢性放射線皮膚障害の像を呈し，左外眼角から上外方にかけては不整形で硬く隆起する疣状角化腫瘤を認めた。病理組織学的に有棘細胞癌と診断し，腫瘍切除・植皮術を施行した。統計から本邦のβ線照射療法による皮膚癌発生例はあま …
NAID 130003378174

Related Pictures

★リンクテーブル★

リンク元	「太田母斑」「Ota's nevus」
関連記事	「O」

「太田母斑」

Nevus of Ota
Classification and external resources
Specialty	oncology
ICD-10	D22.3 (ILDS D22.301)
DiseasesDB	32588
eMedicine	DERM/290
MeSH	D009507
	[edit on Wikidata]