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English Journal

Elevated microRNA-181c and microRNA-30d levels in the enlarged amygdala of the valproic acid rat model of autism.

Olde Loohuis NF1, Kole K2, Glennon JC1, Karel P1, Van der Borg G2, Van Gemert Y2, Van den Bosch D2, Meinhardt J2, Kos A1, Shahabipour F2, Tiesinga P2, van Bokhoven H3, Martens GJ4, Kaplan BB5, Homberg JR1, Aschrafi A6.
Neurobiology of disease.Neurobiol Dis.2015 Aug;80:42-53. doi: 10.1016/j.nbd.2015.05.006. Epub 2015 May 16.
Autism spectrum disorders are severe neurodevelopmental disorders, marked by impairments in reciprocal social interaction, delays in early language and communication, and the presence of restrictive, repetitive and stereotyped behaviors. Accumulating evidence suggests that dysfunction of the amygdal
PMID 25986729

n-3 PUFAs have beneficial effects on anxiety and cognition in female rats: Effects of early life stress.

Pusceddu MM1, Kelly P2, Ariffin N3, Cryan JF4, Clarke G5, Dinan TG6.
Psychoneuroendocrinology.Psychoneuroendocrinology.2015 Aug;58:79-90. doi: 10.1016/j.psyneuen.2015.04.015. Epub 2015 Apr 28.
Stressful life events, especially those in early life, can exert long-lasting changes in the brain, increasing vulnerability to mental illness especially in females. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) play a critical role in the development and function of the central nervous system (CN
PMID 25965872

A quantitative and qualitative review of the effects of testosterone on the function and structure of the human social-emotional brain.

Heany SJ1, van Honk J, Stein DJ, Brooks SJ.
Metabolic brain disease.Metab Brain Dis.2015 Jun 16. [Epub ahead of print]
Social and affective research in humans is increasingly using functional and structural neuroimaging techniques to aid the understanding of how hormones, such as testosterone, modulate a wide range of psychological processes. We conducted a meta-analysis of functional magnetic resonance imaging (fMR
PMID 26073231