神経皮膚炎
- 関
- lichen simplex chronicus
WordNet
- dermatitis in which localized areas (especially the forearms or back of the neck or outer part of the ankle) itch persistently; cause is unknown
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/12/18 19:49:27」(JST)
[Wiki en表示]
| Lichen simplex chronicus |
|
| Micrograph of lichen simplex chronicus. H&E stain. |
| Classification and external resources |
| Specialty |
dermatology |
| ICD-10 |
L28.0 |
| ICD-9-CM |
698.3 |
| DiseasesDB |
31441 |
| MedlinePlus |
000872 |
| eMedicine |
derm/236 |
| MeSH |
D009450 |
|
[edit on Wikidata]
|
Lichen simplex chronicus (LSC) (also known as "Neurodermatitis"[1]) is a skin disorder characterized by chronic itching and scratching.[2] The constant scratching causes thick, leathery, darkened, (lichenified) skin. This condition is associated with many factors, including the scratch-itch cycle, psychological stressors, and atopy. LSC is more common between ages 35 and 50 and is seen approximately twice as often in women compared to men.[3]
Contents
- 1 Signs and symptoms
- 2 Causes
- 3 Diagnosis
- 4 Treatment
- 5 See also
- 6 References
Signs and symptoms
People burdened with LSC report pruritus, followed by uncontrollable scratching of the same body region, excessively.[2] Most common sites of LSC are the sides of the neck, the scalp, ankles, vulva, pubis, scrotum, and extensor sides of the forearms.[3] However, due to the stigma associated with chronic scratching, some patients will not admit to chronic rubbing or abrasion. The skin may become thickened and hyperpigmented (lichenified) as a direct result of chronic exoriation.[3] Typically this period of increased scratching is associated with stressors.
Causes
This is a skin disorder characterized by a self-perpetuating scratch-itch cycle:[4]
- It may begin with something that rubs, irritates, or scratches the skin, such as clothing.
- This causes the person to rub or scratch the affected area. Constant scratching causes the skin to thicken.
- The thickened skin itches, causing more scratching, causing more thickening.
- Affected area may spread rapidly through the rest of the body.
Many hypothesize LSC has a psychosomatic origin.[3] Those predisposed to itch as a response to emotional tensions may be more susceptible to the itch-scratch cycle. It may also be associated with nervousness, anxiety, depression, and other psychological disorders.[5][6] Many people with LSC are aware of the scratching they do during the day, but they might not be aware of the scratching they do in their sleep.[2] LSC is also associated with atopy, or atopic dermatitis (eczema).[2]
Diagnosis
LSC is typically diagnosed by careful observation and history taking.[3] It is easily recognized (see signs and symptoms, and gallery).[2] Biopsies are not necessary, and cannot be used to distinguish LSC from psoriasis.
Treatment
Treatment is aimed at reducing itching and minimizing existing lesions because rubbing and scratching exacerbate LSC. The itching and inflammation may be treated with a lotions or steroid cream (such as triamcinolone or Betamethasone) applied to the affected area of the skin.[7] Nighttime scratching can be reduced with sedatives and antihistamines.[2] SSRIs can effectively reduce the scratching associated with obsessive psychosomatic behaviors.
Gallery
See also
- Pruritus
- List of cutaneous conditions
References
- ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
- ^ a b c d e f Lynch, Peter J. (2004-01-01). "Lichen simplex chronicus (atopic/neurodermatitis) of the anogenital region". Dermatologic Therapy. 17 (1): 8–19. ISSN 1396-0296. PMID 14756886.
- ^ a b c d e Lotti, Torello; Buggiani, Gionata; Prignano, Francesca (2008-01-01). "Prurigo nodularis and lichen simplex chronicus". Dermatologic Therapy. 21 (1): 42–46. doi:10.1111/j.1529-8019.2008.00168.x. ISSN 1529-8019.
- ^ Lee, Michael R.; Shumack, Stephen (2005-11-01). "Prurigo nodularis: a review". The Australasian Journal of Dermatology. 46 (4): 211–218; quiz 219–220. doi:10.1111/j.1440-0960.2005.00187.x. ISSN 0004-8380. PMID 16197418.
- ^ Konuk, Numan; Koca, Rafet; Atik, Levent; Muhtar, Sennur; Atasoy, Nuray; Bostanci, Bora (2007-05-01). "Psychopathology, depression and dissociative experiences in patients with lichen simplex chronicus". General Hospital Psychiatry. 29 (3): 232–235. doi:10.1016/j.genhosppsych.2007.01.006. ISSN 0163-8343.
- ^ Krishnan, Anjeli; Koo, John (2005-07-01). "Psyche, opioids, and itch: therapeutic consequences". Dermatologic Therapy. 18 (4): 314–322. doi:10.1111/j.1529-8019.2005.00038.x. ISSN 1396-0296. PMID 16297003.
- ^ Yosipovitch, Gil; Bernhard, Jeffrey D. (2013-04-25). "Chronic Pruritus". New England Journal of Medicine. 368 (17): 1625–1634. doi:10.1056/NEJMcp1208814. ISSN 0028-4793. PMID 23614588.
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Dermatitis and eczema (L20–L30, 690–693,698)
|
| Atopic dermatitis |
|
| Seborrheic dermatitis |
- Pityriasis simplex capillitii
- Cradle cap
|
Contact dermatitis
(allergic, irritant) |
- plants: Urushiol-induced contact dermatitis
- African blackwood dermatitis
- Tulip fingers
- other: Abietic acid dermatitis
- Diaper rash
- Airbag dermatitis
- Baboon syndrome
- Contact stomatitis
- Protein contact dermatitis
|
| Eczema |
- Autoimmune estrogen dermatitis
- Autoimmune progesterone dermatitis
- Breast eczema
- Ear eczema
- Eyelid dermatitis
- Topical steroid addiction
- Hand eczema
- Chronic vesiculobullous hand eczema
- Hyperkeratotic hand dermatitis
- Autosensitization dermatitis/Id reaction
- Candidid
- Dermatophytid
- Molluscum dermatitis
- Circumostomy eczema
- Dyshidrosis
- Juvenile plantar dermatosis
- Nummular eczema
- Nutritional deficiency eczema
- Sulzberger–Garbe syndrome
- Xerotic eczema
|
Pruritus/Itch/
Prurigo |
- Lichen simplex chronicus/Prurigo nodularis
- by location: Pruritus ani
- Pruritus scroti
- Pruritus vulvae
- Scalp pruritus
- Drug-induced pruritus
- Hydroxyethyl starch-induced pruritus
- Senile pruritus
- Aquagenic pruritus
- Adult blaschkitis
- due to liver disease
- Biliary pruritus
- Cholestatic pruritus
- Prion pruritus
- Prurigo pigmentosa
- Prurigo simplex
- Puncta pruritica
- Uremic pruritus
|
| Other |
- substances taken internally: Bromoderma
- Fixed drug reaction
- Nummular dermatitis
- Pityriasis alba
- Papuloerythroderma of Ofuji
|
UpToDate Contents
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English Journal
- Real-life effect of classical homeopathy in the treatment of allergies: A multicenter prospective observational study.
- Gründling C, Schimetta W, Frass M.SourceGeneral and Homeopathic Medical Practice, Enns, Austria. praxis@drgruendling.at
- Wiener klinische Wochenschrift.Wien Klin Wochenschr.2012 Jan;124(1-2):11-7. Epub 2011 Dec 8.
- OBJECTIVE: The prevalence of allergic disorders in western industrialized countries has steadily increased during the last three decades. Public acceptance of complementary treatment methods is high. The aim of this study was to assess the real-life efficacy of classical homeopathic treatment and th
- PMID 22138796
- Verrucous carcinoma arising in lichen simplex chronicus.
- Cao M, Lu X, Luo D, Lin J, He Y.
- European journal of dermatology : EJD.Eur J Dermatol.2011 Jul-Aug;21(4):605-7.
- PMID 21719404
Japanese Journal
- 東北地方にある特異な泉質の温泉とそれらの皮膚科的適用
- Localized Cutaneous Amyloidosis Simulating Lichen Simplex Chronicus
- Klinische Verlaufsbeobachtungen bei Neurodermitis atopica nach dem Kleinkindesalter. Eine katamnestische Untersuchung anhand von 121 Fallen. [Clinical course of atopic neurodermatitis. A catamnestic study of 121 cases.]
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Related Pictures
★リンクテーブル★
[★]
- 英
- neurodermatitis
- 関
- 慢性単純性苔癬