English Journal

Further development of a neurobehavioral profile of fetal alcohol spectrum disorders.

Mattson SN, Roesch SC, Glass L, Deweese BN, Coles CD, Kable JA, May PA, Kalberg WO, Sowell ER, Adnams CM, Jones KL, Riley EP.SourceCenter for Behavioral Teratology , San Diego State University, San Diego, California; Department of Psychology , San Diego State University, San Diego, California.
Alcoholism, clinical and experimental research.Alcohol Clin Exp Res.2013 Mar;37(3):517-28. doi: 10.1111/j.1530-0277.2012.01952.x. Epub 2012 Sep 13.
BACKGROUND: Heavy prenatal alcohol exposure (AE) results in a broad array of neurobehavioral deficits. Recent research has focused on identification of a neurobehavioral profile or profiles that will improve the identification of children affected by AE. This study aimed to build on our preliminary
PMID 22974253

Exploring the interface of neurobehaviorally linked personality dimensions and personality organization in borderline personality disorder: the Multidimensional Personality Questionnaire and Inventory of Personality Organization.

Lenzenweger MF, McClough JF, Clarkin JF, Kernberg OF.SourceDepartment of Psychology, Science IV, The State University of New York at Binghamton, Binghamton, NY 13902, USA. mlenzen@binghamton.edu
Journal of personality disorders.J Pers Disord.2012 Dec;26(6):902-18. doi: 10.1521/pedi.2012.26.6.902.
Advances in our understanding of complex psychopathology will likely benefit from approaches to mind, brain, and behavior that seek to (a) specify those general neurobehavioral processes underpinning pathology and (b) bridge to other process-based models of psychopathology at different levels of ana
PMID 23281675

Exploring the Interface of Neurobehaviorally Linked Personality Dimensions and Personality Organization in Borderline Personality Disorder: The Multidimensional Personality Questionnaire and Inventory of Personality Organization.

Lenzenweger MF, McClough JF, Clarkin JF, Kernberg OF.AbstractAdvances in our understanding of complex psychopathology will likely benefit from approaches to mind, brain, and behavior that seek to (a) specify those general neurobehavioral processes underpinning pathology and (b) bridge to other process-based models of psychopathology at different levels of analysis. Well-defined neurobehavioral processes (e.g., positive emotionality, negative emotionality, nonaffective constraint, fear, affiliation) and their phenotypic indicators are firmly rooted in neural substrates (Depue & Lenzenweger, 2005). Furthermore, long-studied psychodynamic psychological processes, such as identity diffusion, primitive psychological defensive functioning, and reality-testing dimensions, are important to understanding personality pathology (Kernberg & Caligor, 2005). Both theoretical perspectives view the cardinal processes involved in the determination of personality disorders (PDs) as relevant across existing PD diagnostic entities. The authors examined relationships between psychometric indicators of these two sets of processes, the neurobehavioral and the psychodynamic, in a well-characterized sample of individuals with borderline personality disorder (BPD; N = 92). In bridging these two levels of analysis, the authors found that the alienation, aggression, and absorption constructs represent important linkages to the psychodynamic processes, especially primitive psychological defenses and reality-testing impairments. These results are discussed in terms of their potential for joining these two domains of analysis-a neurobehaviorally informed view of personality and the psychodynamic-in efforts to (a) foster a process-oriented approach, (b) resolve heterogeneity, and (c) facilitate identification of endophenotypes in BPD. The heuristic value of this approach for understanding other forms of psychopathology is also discussed.
Journal of personality disorders.J Pers Disord.2012 Aug 28. [Epub ahead of print]
Advances in our understanding of complex psychopathology will likely benefit from approaches to mind, brain, and behavior that seek to (a) specify those general neurobehavioral processes underpinning pathology and (b) bridge to other process-based models of psychopathology at different levels of ana
PMID 22928851