WordNet

(physiology) the normal degeneration and death of living cells (as in various epithelial cells) (同)cell_death

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/01/15 00:40:25」(JST)

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Necrobiosis is defined as the physiological death of a cell, and can be caused by certain conditions such as basophilia, erythema or the presence of a tumor. It is identified both with^[1] and without necrosis.

It is associated with necrobiosis lipoidica and granuloma annulare.

Necrobiosis differs from apoptosis, which causes the death of a damaged cell in order to protect the body from harm.

References[edit]

^ eMedicine/Stedman Medical Dictionary Lookup!

External links[edit]

"Necrobiosis" at Dorland's Medical Dictionary

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1. リポイド類壊死症 necrobiosis lipoidica
2. 類壊死性黄色肉芽腫 necrobiotic xanthogranuloma
3. 環状肉芽腫 granuloma annulare
4. うっ滞性皮膚炎 stasis dermatitis
5. サルコイドーシスの皮膚症状 cutaneous manifestations of sarcoidosis

English Journal

Necrobiosis lipoidica occurring in a patient with rheumatoid arthritis on concurrent tumor necrosis factor-α inhibitor therapy.

Chung CG1, Rosengrant A, Helm KF, Shupp DL.
International journal of dermatology.Int J Dermatol.2014 Apr 2. doi: 10.1111/ijd.12309. [Epub ahead of print]
PMID 24697547

Cutaneous Manifestations in Children with Diabetes Mellitus and Obesity.

Baselga Torres E1, Torres-Pradilla M2.Author information 1Dermatología pediátrica, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España; Dermatología pediátrica, Clínica Dermatológica Multidisciplinar DERMIK, Barcelona, España. Electronic address: dra.baselga@gmail.com.2Dermatología pediátrica, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España; Dermatología pediátrica, Clínica Dermatológica Multidisciplinar DERMIK, Barcelona, España.AbstractObesity and diabetes are chronic diseases that affect people all over the world, and their incidence is increasing in both children and adults. Clinically, they affect a number of organs, including the skin. The cutaneous manifestations caused or aggravated by obesity and diabetes are varied and usually bear some relation to the time that has elapsed since the onset of the disease. They include soft fibromas, acanthosis nigricans, striae, xerosis, keratosis pilaris, plantar hyperkeratosis, fungal and bacterial skin infections, granuloma annulare, necrobiosis lipoidica, psoriasis, and atopic dermatitis. In this review article we present the skin changes found in children with diabetes mellitus and obesity and related syndromes and highlight the importance of the skin as a tool for establishing clinical suspicion and early diagnosis of systemic disease.
Actas dermo-sifiliograficas.Actas Dermosifiliogr.2014 Mar 31. pii: S0001-7310(14)00071-4. doi: 10.1016/j.ad.2013.11.014. [Epub ahead of print]
Obesity and diabetes are chronic diseases that affect people all over the world, and their incidence is increasing in both children and adults. Clinically, they affect a number of organs, including the skin. The cutaneous manifestations caused or aggravated by obesity and diabetes are varied and usu
PMID 24698434