ナルセイン
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/11/04 18:46:07」(JST)
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Narceine |
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IUPAC name
6-({6-[2-(dimethylamino)ethyl]-4-methoxy-1,3-benzodioxol-5-yl}acetyl)-2,3-dimethoxybenzoic acid
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Identifiers |
CAS number |
131-28-2 |
PubChem |
8564 |
ChemSpider |
8246 |
UNII |
CTT09X2F1M |
EC number |
235-480-2 |
KEGG |
C09591 |
Jmol-3D images |
Image 1 |
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CN(C)CCC1=CC2=C(C(=C1CC(=O)C3=C(C(=C(C=C3)OC)OC)C(=O)O)OC)OCO2
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InChI=1S/C23H27NO8/c1-24(2)9-8-13-10-18-22(32-12-31-18)20(29-4)15(13)11-16(25)14-6-7-17(28-3)21(30-5)19(14)23(26)27/h6-7,10H,8-9,11-12H2,1-5H3,(H,26,27)
Key: DEXMFYZAHXMZNM-UHFFFAOYSA-N
InChI=1/C23H27NO8/c1-24(2)9-8-13-10-18-22(32-12-31-18)20(29-4)15(13)11-16(25)14-6-7-17(28-3)21(30-5)19(14)23(26)27/h6-7,10H,8-9,11-12H2,1-5H3,(H,26,27)
Key: DEXMFYZAHXMZNM-UHFFFAOYAJ
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Properties |
Molecular formula |
C23H27NO8 |
Molar mass |
445.46 g mol−1 |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa) |
Infobox references |
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Narceine is an opium alkaloid produced by the Papaver somniferum (opium poppy) plant.[1] It is a bitter, crystalline compound with narcotic effects and was formerly used as a substitute for morphine. Its name is derived from the Greek νάρκη (nárkē), meaning numbness, and the postfix -ine referring to an alkaloid.
See also
- Noscapine, a related alkaloid
References
- ^ van Itallie, L. (1946). "Investigations on poppies". Annales Pharmaceutiques Francaises 4: 156–160.
Opium components
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Alkaloids |
- 16-Hydroxythebaine
- Berberine
- Canadine
- Codamine
- Coptisine
- Coreximine
- Cycloartenol
- Cycloartenone
- Cyclolaudenol
- Dehydroreticuline
- Dihydrosanguinarine
- Glaucine
- Isoboldine
- Isocorypalmine
- Laudanidine
- Magnoflorine
- Narceine
- Narceinone
- Norlaudanosoline
- Norsanguinarine
- Oripavine
- Oxysanguinarine
- Palaudine
- Papaverrubine B (O-methyl-porphyroxine)
- Papaverrubine C (epiporphyroxine)
- Reticuline
- Salutaridine (sinoacutine)
- Sanguinarine
- Scoulerine
- Somniferine
- Stepholidine
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Morphine group
(Phenanthrenes. Includes opioids) |
- Codeine
- Morphine
- Narcotoline
- Neopine
- Perparin
- Papaverrubine D (porphyroxine)
- Pseudocodeine
- Pseudomorphine
- Thebaine
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Isoquinolines |
- Cotarnine
- Eupaverine
- Hydrocotarnine
- Laudanosine
- Laudanine
- Noscapine (narcotine)
- Papaverine
- Papaveraldine
- Xanthaline
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Protopine group |
- α-Allocryptopine
- α-Fagarine
- Corycavamine
- Corycavine
- Cryptopine
- Protopine
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Tetrahydroprotoberberine group |
- Corydaline
- Corybulbine
- Isocorybulbine
- Capaurine
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Aporphine group |
- Dicentrine
- Glaucine
- Corytuberine
- Cularine
- Corydine
- Isocorydine
- Bulbocapnine
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Phtalide-isoquinolines |
- Adulmine
- Bicuculline
- Bicucine
- Corlumine
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α-Naphthaphenanthridines |
- Chelidonine
- β-Homochelidonoine
- Chelerythrine
- Sanguinarine
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Other components |
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English Journal
- Non-addictive opium alkaloids selectively induce apoptosis in cancer cells compared to normal cells.
- Afzali M1, Ghaeli P2, Khanavi M3, Parsa M4, Montazeri H5, Ghahremani MH6, Ostad SN7.
- Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences.Daru.2015 Feb 20;23:16. doi: 10.1186/s40199-015-0101-1.
- BACKGROUND: Cytotoxic effects of some of the members of papaveraceae family have been reported in Iranian folk medicine. Recent reports has indicated that alkaloids fraction of opium may be responsible for its cytotoxic effect; however, the mechanism of this effect is not fully understood. This stud
- PMID 25890335
- [Nursing cooperation on circulation restore during microvascular submandibular gland transfer].
- Kang XW1, Rong C, Liu J.
- Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology.Hua Xi Kou Qiang Yi Xue Za Zhi.2011 Jun;29(3):261-3.
- OBJECTIVE: To summarize the cooperative measures on circulation restore during the operation of microvascular submandibular gland transfer.METHODS: Fifty-six cases of microvascular submandibular gland transfer were performed in Peking University School & Hospital of Stomatology from January 2005
- PMID 21776850
- Applicability of ultra-performance liquid chromatography-tandem mass spectrometry for heroin profiling.
- Lurie IS1, Toske SG.
- Journal of chromatography. A.J Chromatogr A.2008 Apr 25;1188(2):322-6. doi: 10.1016/j.chroma.2008.03.011. Epub 2008 Mar 18.
- The applicability of ultra- performance liquid chromatography tandem-mass spectrometry (UPLC-MS/MS) for heroin profiling is described. The coupling of the high separation power of UPLC with the highly selective and sensitive detection of MS/MS is well suited for heroin profiling. An Acquity UPLC BEH
- PMID 18374345
Japanese Journal
- 高速液体クロマトグラフィーによる塩酸アヘンアルカロイドの定量(<特集>医薬品の分析)
- 千葉 良子,石井 耀子
- 分析化学 35(3), 173-176, 1986-03-05
- 高速液体クロマトグラフィー(HPLC)を用いて,高感度と迅速化を目的として,日本薬局方第10改正に収載されている塩酸アヘンアルカロイド中の主な5種類のアルカロイド(モルヒネ,コデイン,ナルセイン,ノスカピン,パパベリン)の同時分離定量法を確立した.すなわち試料の塩酸アヘンアルカロイドはメタノールに溶解して,HPLC定量用試料溶液とし,直接カラムに注入する.カラムは逆相用の日立ゲル3056(150m …
- NAID 110002909307
- 深間内 久雄 [他],出野 竜子,三本木 則子
- 藥學雜誌 90(8), 1039-1047, 1970-08-25
- … The six principal alkaloids of opium can be separated into three groups by sequential extractions with solvents as follows : the first group (noscapine, papaverine and thebaine) comes in chloroform, the second group (codeine and thebaine) in benzene, while the third group (morphine and narceine) remains in the aqueous phase. … narceine : 1.36,99.0% ; …
- NAID 110003654494
Related Links
- narceineとは。意味や和訳。[名詞] 〔薬学〕 ナルセイン C23H27NO8:麻酔性アルカロイド;アヘンに含まれ,平滑筋の弱い弛緩しかん剤として働く. (また narceen)[語源]<フランス語 narcéine(1832),不規則変化をして<ギリシャ語 nárkē ...
- 1件 の用語解説(narceine の意味・用語解説を検索) プログレッシブ英和中辞典(第4版) の解説 nar・ce・ine /n rsiì n/ [名][U]《薬学》ナルセイン:アヘンに含まれる麻酔性アルカロイド. 出典|小学館 この辞書の凡例を見る 編集主幹 ...
Related Pictures
★リンクテーブル★
[★]
- 英
- narcotic narcotics, narcotic drugs
- ラ
- narcotica
- 関
日本の法医学上の定義
分類
- SLE.62
麻薬性鎮痛薬 narcotic analgesics
- 1. アヘンアルカロイド系 opium alkaloids (いわゆるオピオイド)
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- アヘン opium:複数のアルカロイドが含まれている
中枢神経興奮薬 stimulants
- 3. コカアルカロイド系 coca alkaloids
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