English Journal

Arsenic Promotes NF-Κb-Mediated Fibroblast Dysfunction and Matrix Remodeling to Impair Muscle Stem Cell Function.

Zhang C1, Ferrari R1, Beezhold K2, Stearns-Reider K1, D'Amore A3, Haschak M1, Stolz D4, Robbins PD5, Barchowsky A2,6, Ambrosio F1,7,8.
Stem cells (Dayton, Ohio).Stem Cells.2016 Mar;34(3):732-42. doi: 10.1002/stem.2232. Epub 2016 Jan 8.
Arsenic is a global health hazard that impacts over 140 million individuals worldwide. Epidemiological studies reveal prominent muscle dysfunction and mobility declines following arsenic exposure; yet, mechanisms underlying such declines are unknown. The objective of this study was to test the novel
PMID 26537186

Prenatal muscle development in a mouse model for the secondary dystroglycanopathies.

Kim J1, Hopkinson M1, Kavishwar M1, Fernandez-Fuente M1, Brown SC1.
Skeletal muscle.Skelet Muscle.2016 Feb 19;6:3. doi: 10.1186/s13395-016-0073-y. eCollection 2016.
BACKGROUND: The defective glycosylation of α-dystroglycan is associated with a group of muscular dystrophies that are collectively referred to as the secondary dystroglycanopathies. Mutations in the gene encoding fukutin-related protein (FKRP) are one of the most common causes of secondary dystrogl
PMID 26900448

Sequential identification of a degradable phosphate glass scaffold for skeletal muscle regeneration.

Shah R1, Ready D, Knowles JC, Hunt NP, Lewis MP.
Journal of tissue engineering and regenerative medicine.J Tissue Eng Regen Med.2014 Oct;8(10):801-10. doi: 10.1002/term.1581. Epub 2012 Oct 22.
Tissue engineering has the potential to overcome limitations associated with current management of skeletal muscle defects. This study aimed to sequentially identify a degradable phosphate glass scaffold for the restoration of muscle defects. A series of glass compositions were investigated for the
PMID 23086759