myoepithelioma

筋上皮腫

関

myoepithelial tumor

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/02/12 02:59:49」(JST)

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Myoepithelioma of the head and neck
Micrograph of a myoepithelioma. H&E stain.
Classification and external resources

Myoepithelioma of the head and neck, also myoepithelioma, is a salivary gland tumour of the head and neck that is usually benign.

As the name suggests, it consists of myoepithelial cells. Classically, they are found in the parotid gland or palate. A similar tumor type may be found in the tongue, referred to as ectomesenchymal chondromyxoid tumor.

Diagnosis

Myoepitheliomas are diagnosed from an examination of the tissue by a pathologist.

Pathology

The myoepithelial cells may be spindled, plasmacytoid, eithelioid or clear. Tubules or epithelium are absent, or present in a small amount (<5%) by definition. Tumours with myoepithelial cells and a large amount of tubules are classified as pleomorphic adenomas (which must also contain the characteristic chondromyxoid stroma, which is normally absent in myoepithelioma).

Treatment

Benign myoepithelioma are treated with simple excision. They are less prone to recurrence than pleomorphic adenoma.

See also

• Pleomorphic adenoma
• Ectomesenchymal Chondromyxoid tumor

Additional images

• Low mag.

• High mag.

UpToDate Contents

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• 1. 頭頸部腫瘍の病理 pathology of head and neck neoplasms

English Journal

• EWSR1-ATF1 chimeric transcript in a myoepithelial tumor of soft tissue: a case report.

• Flucke U, Mentzel T, Verdijk MA, Slootweg PJ, Creytens DH, Suurmeijer AJ, Tops BB.SourceDepartment of Pathology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
• Human pathology.Hum Pathol.2012 May;43(5):764-8. Epub 2011 Dec 7.
• Soft tissue myoepithelial tumors, a recently defined entity, include benign and malignant lesions showing a considerable morphological and immunohistochemical heterogeneity. EWSR1 rearrangements are well recognized in this tumor type, and some of the partner genes have been identified. Herein we des
• PMID 22154050

• Is human papilloma virus associated with salivary gland neoplasms? An in situ-hybridization study.

• Hafed L, Farag H, Shaker O, El-Rouby D.SourceOral Pathology Department, Faculty of Oral and Dental Medicine, Cairo University, Mathaf-El-Manial Street, El-Manial, Cairo, Egypt.
• Archives of oral biology.Arch Oral Biol.2012 Apr 25. [Epub ahead of print]
• OBJECTIVE: HPV can infect cells of epithelial origin and is closely associated with carcinomas. Studies investigating its presence in salivary gland neoplasms are few and conflicting.METHODS: Detection of HPV types 16 & 18 was done on 34 formalin-fixed, paraffin-embedded archival material of dif
• PMID 22542162

Japanese Journal

• 症例報告 足底に生じた筋上皮腫の1例

• 水谷 友哉,村尾 和俊,久保 宜明 [他]
• 臨床皮膚科 66(11), 875-878, 2012-10
• NAID 40019456905

• 症例 耳下腺に発生した筋上皮腫の1例

• 内田 崇之,牧 昌利,増澤 源造 [他]
• 形成外科 55(4), 427-432, 2012-04
• NAID 40019255435

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筋上皮腫瘍

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myoepithelioma