expressed without speech; "a mute appeal"; "a silent curse"; "best grief is tongueless"- Emily Dickinson; "the words stopped at her lips unsounded"; "unspoken grief"; "choking exasperation and wordless shame"- Thomas Wolfe (同)tongueless, unspoken, wordless
a device used to soften the tone of a musical instrument
a deaf person who is unable to speak (同)deaf-mute, deaf-and-dumb person
Journal of biotechnology.J Biotechnol.2014 Jun 4. pii: S0168-1656(14)00269-7. doi: 10.1016/j.jbiotec.2014.05.023. [Epub ahead of print]
Pyruvate dehydrogenase and oxoglutarate dehydrogenase catalyze key reactions in central metabolism. In Corynebacterium glutamicum and related bacteria like Mycobacterium tuberculosis both activities reside in a novel protein supercomplex with the fusion protein OdhA catalyzing the conversion of oxog
T cells redirected to interleukin-13Rα2 with interleukin-13 mutein-chimeric antigen receptors have anti-glioma activity but also recognize interleukin-13Rα1.
Krebs S1, Chow KK2, Yi Z1, Rodriguez-Cruz T1, Hegde M3, Gerken C1, Ahmed N4, Gottschalk S5.
Cytotherapy.Cytotherapy.2014 May 16. pii: S1465-3249(14)00506-4. doi: 10.1016/j.jcyt.2014.02.012. [Epub ahead of print]
BACKGROUND AIMS: Outcomes for patients with glioblastoma remain poor despite aggressive multimodal therapy. Immunotherapy with genetically modified T cells expressing chimeric antigen receptors (CARs) targeting interleukin (IL)13Rα2, human epidermal growth factor receptor 2, epidermal growth factor
Therapeutic potential of leptin receptor modulators.
Leggio A1, Catalano S1, De Marco R1, Barone I1, Andò S2, Liguori A3.
European journal of medicinal chemistry.Eur J Med Chem.2014 May 6;78:97-105. doi: 10.1016/j.ejmech.2014.03.048. Epub 2014 Mar 16.
Leptin, a pleiotropic molecule mainly produced by adipose tissue, was first discovered as a hormone controlling body weight and energy expenditure. In addition, leptin can modulate several processes in peripheral tissues such as immune response, fertility, hematopoiesis and carcinogenesis. The devel
Engineering of novel tamavidin 2 muteins with lowered isoelectric points and lowered non-specific binding properties(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
Journal of bioscience and bioengineering 114(5), 485-489, 2012-11
… In particular, one mutein, tamavidin-R104EK141E, which had the lowest isoelectric point (5.8-6.2) among avidin, streptavidin and tamavidin 2, displayed the lowest non-specific binding. … The affinity of this mutein to biotin was high, comparable with that of tamavidin 2. …
Tumor necrosis factor-alpha (TNF-a) has been expected to be a promising new antitumor agent, but toxic side effects by the systemic administration of TNF-a limit its clinical application. In this stud …
Mutein definition, a mutationally altered protein. See more. Thesaurus Translate Puzzles & Games Reference Word of the Day Blog Slideshows Apps by Dictionary My Account Log Out Log In follow Dictionary.com Dictionary ...
mu·tein (myōō′tēn′, -tē-ĭn) n. A protein arising as a result of a mutation. mutein [myo o ′tē·in, m(y)o o ′tēn] a protein molecule that results from a mutation. mutein A protein that results from the translation of a mutation. mu·tein (myū'tēn), ...