単核性貧食細胞系

WordNet

(physical chemistry) a sample of matter in which substances in different phases are in equilibrium; "in a static system oil cannot be replaced by water on a surface"; "a system generating hydrogen peroxide"
instrumentality that combines interrelated interacting artifacts designed to work as a coherent entity; "he bought a new stereo system"; "the system consists of a motor and a small computer"
a group of independent but interrelated elements comprising a unified whole; "a vast system of production and distribution and consumption keep the country going" (同)scheme
a complex of methods or rules governing behavior; "they have to operate under a system they oppose"; "that language has a complex system for indicating gender" (同)system of rules
a group of physiologically or anatomically related organs or parts; "the body has a system of organs for digestion"
a procedure or process for obtaining an objective; "they had to devise a system that did not depend on cooperation"
the living body considered as made up of interdependent components forming a unified whole; "exercise helped him get the alcohol out of his system"
a cell that engulfs and digests debris and invading microorganisms (同)scavenger cell
having only one nucleus (同)mononucleate

PrepTutorEJDIC

〈C〉(関連した部分から成る)『体系』,系統,組織[網],装置 / 〈C〉(教育・政治などの)『制度』,機構;《the~》体制 / 〈C〉(思想・学問などの)『体系』,学説 / 〈C〉(…の)『方法』,方式,やり方《+of doing》 / 〈U〉正しい方針(筋道,順序) / 〈U〉《the~》(身体の)組織,系統 / 〈U〉《the~,one's~》身体,全身
食細胞(異物・バクテリアなどの細胞を処理する血球)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/06/02 01:35:46」(JST)

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The mononuclear phagocyte system (MPS) is a part of the immune system that consists of the phagocytic cells^[1] located in reticular connective tissue. The cells are primarily monocytes and macrophages, and they accumulate in lymph nodes and the spleen. The Kupffer cells of the liver and tissue histiocytes are also part of the MPS.

"Reticuloendothelial system" is an older term for the mononuclear phagocyte system, but it is used less commonly now, as it is understood that most endothelial cells are not macrophages.^[2]

The spleen is the largest unit of the mononuclear phagocyte system. The monocyte is formed in the bone marrow and transported by the blood; it migrates into the tissues, where it transforms into a histiocyte or a macrophage. Macrophages are diffusely scattered in the connective tissue and in liver (Kupffer cells), spleen and lymph nodes (sinus histiocytes), lungs (alveolar macrophages), and central nervous system (microglia). The half-life of blood monocytes is about 1 day, whereas the life span of tissue macrophages is several months or years. The mononuclear phagocyte system is part of both humoral and cell-mediated immunity. The mononuclear phagocyte system has an important role in defense against microorganisms, including mycobacteria, fungi, bacteria, protozoa, and viruses. Macrophages remove senescent erythrocytes, leukocytes, and megakaryocytes by phagocytosis and digestion.

Functions [edit]

Formation of new red blood cells (RBCs) and white blood cells (WBCs).
Destruction of old RBCs and WBCs
Formation of antibodies.
Formation of plasma proteins.
Formation of bile pigments.
Storage of iron. In the liver, Kupffer cells store excess iron from catabolism of heme from the breakdown of red blood cells. In bone marrow and spleen, iron is stored in MPS cells mostly as ferritin; in iron overload states, most of the iron is stored as hemosiderin.

References [edit]

^ Mononuclear Phagocyte System at the US National Library of Medicine Medical Subject Headings (MeSH)
^ Inderbir Singh (2006). Textbook of human histology. Jaypee Brothers Publishers. pp. 90–. ISBN 978-81-8061-809-3. Retrieved 12 November 2010.

External links [edit]

550502460 at GPnotebook
Immunology at MCG 1/reticulo

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UpToDate Contents

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English Journal

Identification of IL-34 in teleost fish: Differential expression of rainbow trout IL-34, MCSF1 and MCSF2, ligands of the MCSF receptor.

Wang T, Kono T, Monte MM, Kuse H, Costa MM, Korenaga H, Maehr T, Husain M, Sakai M, Secombes CJ.SourceScottish Fish Immunology Research Centre, School of Biological Sciences, University of Aberdeen, Aberdeen AB24 2TZ, UK. Electronic address: t.h.wang@abdn.ac.uk.
Molecular immunology.Mol Immunol.2013 Apr;53(4):398-409. doi: 10.1016/j.molimm.2012.09.008. Epub 2012 Oct 23.
The mononuclear phagocyte system is composed of monocytes, macrophages and dendritic cells and has crucial roles in inflammation, autoimmunity, infection, cancer, organ transplantation and in maintaining organismal homeostasis. Interleukin-34 (IL-34) and macrophage colony stimulating factor (MCSF),
PMID 23099477

Radioisotope post-labeling upconversion nanophosphors for in vivo quantitative tracking.

Sun Y, Liu Q, Peng J, Feng W, Zhang Y, Yang P, Li F.SourceDepartment of Chemistry & Institutes of Biomedical Sciences, Fudan University, 220 Handan Road, Shanghai 200433, PR China.
Biomaterials.Biomaterials.2013 Mar;34(9):2289-95. doi: 10.1016/j.biomaterials.2012.11.047. Epub 2012 Dec 27.
Lanthanide based upconversion nanophosphors (UCNPs) attracted increasing attention for potential applications in bioimaging, while its in vivo behaviors are not clear until now due to no available quantification imaging tools. Herein, we developed a unique rare-earth cation-exchange-based postlabel
PMID 23274071