WordNet

any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"

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1. 脊髄小脳変性症 the spinocerebellar ataxias
2. プロテインＳ欠乏症 protein s deficiency
3. プロテインＣ欠乏症 protein c deficiency
4. 第V因子ライデンと活性化プロテインC抵抗性 factor v leiden and activated protein c resistance
5. 肥大型心筋症：遺伝子変異および臨床遺伝子検査 hypertrophic cardiomyopathy gene mutations and clinical genetic testing

Fabrication and characterization of Pickering emulsions and oil gels stabilized by highly charged zein/chitosan complex particles (ZCCPs).

Wang LJ1, Yin SW2, Wu LY3, Qi JR4, Guo J4, Yang XQ5.
Food chemistry.Food Chem.2016 Dec 15;213:462-9. doi: 10.1016/j.foodchem.2016.06.119. Epub 2016 Jul 1.
Herein, we reported a facile method to fabricate ultra-stable, surfactant- and antimicrobial-free Pickering emulsions by designing and modulating emulsions' interfaces via zein/chitosan colloid particles (ZCCPs). Highly charged ZCCPs with neutral wettability were produced by a facile anti-solvent pr
PMID 27451205

Involvement of Ubiquitin-Editing Protein A20 in Modulating Inflammation in Rat Cochlea Associated with Silver Nanoparticle-Induced CD68 Upregulation and TLR4 Activation.

Feng H1, Pyykkö I1, Zou J2,3.
Nanoscale research letters.Nanoscale Res Lett.2016 Dec;11(1):240. doi: 10.1186/s11671-016-1430-9. Epub 2016 May 4.
Silver nanoparticles (AgNPs) were shown to temporarily impair the biological barriers in the skin of the external ear canal, mucosa of the middle ear, and inner ear, causing partially reversible hearing loss after delivery into the middle ear. The current study aimed to elucidate the molecular mecha
PMID 27142878

Hsp90 directly interacts, in vitro, with amyloid structures and modulates their assembly and disassembly.

Schirmer C1, Lepvrier E1, Duchesne L2, Decaux O1, Thomas D1, Delamarche C1, Garnier C3.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 Nov;1860(11 Pt A):2598-609. doi: 10.1016/j.bbagen.2016.07.033. Epub 2016 Aug 3.
BACKGROUND: The 90kDa heat shock protein (Hsp90) participates in regulating the homeostasis of cellular proteins and was considered one of the key chaperones involved in the control and regulation of amyloid deposits. Hsp90 interacts with the amyloid protein tau through tau aggregation-prone regions
PMID 27495389

Atg18 phosphoregulation controls organellar dynamics by modulating its phosphoinositide-binding activity

Tamura Naoki,Oku Masahide,Ito Moemi,Noda Nobuo N,Inagaki Fuyuhiko,Sakai Yasuyoshi
The Journal of Cell Biology 202(4), 685-698, 2013-08-12
… 2013-08-12.The PROPPIN family member Atg18 is a phosphoinositide-binding protein that is composed of a seven β-propeller motif and is part of the conserved autophagy machinery. … This study reveals how the phosphoinositide-binding activity of the PROPPIN family protein Atg18 is regulated at the membrane association domain and highlights the importance of such phosphoregulation in coordinated intracellular reorganization. …
NAID 120005312146

Screening of Isoquinoline Alkaloids for Potent Lipid Metabolism Modulation with Caenorhabditis elegans

CHOW Yit-Lai,SATO Fumihiko
Bioscience, Biotechnology, and Biochemistry, 2013
… Sanguinarine, like berberine, reduced lipid accumulation through AMP-activated protein kinase activation. … elegans for the purpose of lipid-modulating chemical screening and characterization of the underlying mechanisms is discussed. …
NAID 130003381957

Fucosylated Chondroitin Sulfate from Sea Cucumber in Combination with Rosiglitazone Improved Glucose Metabolism in the Liver of the Insulin-Resistant Mice

HU Shiwei,CHANG Yaoguang,WANG Jingfeng,XUE Changhu,LI Zhaojie,WANG Yuming
Bioscience, Biotechnology, and Biochemistry, 2013
… In additionally, it increased the mRNA expression of insulin receptors, insulin receptor substrate 2, phosphatidylinositol 3 kinase (PI3K), protein kinase B (PKB), and glycogen synthase, and inhibited glycogen synthase kinase 3β(GSK-3β) mRNA expression in the liver. … This suggests that CHS/RSG treatment improves glucose metabolism by modulating metabolic enzymes and strengthening the PI3K/PKB/GSK-3β signal pathway mediated by insulin at the transcriptional level. …
NAID 130003381937