WordNet

a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
an agent that triggers mitosis

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1. T細胞受容体シグナル伝達 t cell receptor signaling
2. 免疫不全症を引き起こすCD3／T細胞受容体複合体疾患 cd3 t cell receptor complex disorders causing immunodeficiency
3. インスリン様成長因子 Iの生理学 physiology of insulin like growth factor i
4. インスリン作用 insulin action
5. 常染色体優性多発性嚢胞腎の経過および治療 course and treatment of autosomal dominant polycystic kidney disease

Brain-derived neurotrophic factor and glucocorticoids: Reciprocal influence on the central nervous system.

Numakawa T, Adachi N, Richards M, Chiba S, Kunugi H.SourceDepartment of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP), Tokyo 187-8502, Japan; Core Research for Evolutional Science and Technology Program (CREST), Japan Science and Technology Agency (JST), Saitama 332-0012, Japan. Electronic address: numakawa@ncnp.go.jp.
Neuroscience.Neuroscience.2013 Jun 3;239:157-72. doi: 10.1016/j.neuroscience.2012.09.073. Epub 2012 Oct 13.
Brain-derived neurotrophic factor (BDNF) has multiple roles in the central nervous system (CNS), including maintaining cell survival and regulation of synaptic function. In CNS neurons, BDNF triggers activation of phospholipase Cγ (PLCγ), mitogen-activated protein/extracellular signal-regulated ki
PMID 23069755

Endothelin-1 enhances cell migration through COX-2 up-regulation in human chondrosarcoma.

Wu MH, Chen LM, Hsu HH, Lin JA, Lin YM, Tsai FJ, Tsai CH, Huang CY, Tang CH.SourceGraduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan.
Biochimica et biophysica acta.Biochim Biophys Acta.2013 Jun;1830(6):3355-64. doi: 10.1016/j.bbagen.2013.03.014. Epub 2013 Mar 21.
BACKGROUND: Chondrosarcoma is a type of highly malignant tumor with a potent capacity of local invasion and distant metastasis. The effect of endothelin-1 (ET-1) on migration activity in human chondrosarcoma cells is not clearly understood. Here, we found that ET-1 increased the migration and expres
PMID 23523690

Inhibition of c-Jun NH2-terminal kinase stimulates mu opioid receptor expression via p38 MAPK-mediated nuclear NF-κB activation in neuronal and non-neuronal cells.

Wagley Y, Hwang CK, Lin HY, Kam AF, Law PY, Loh HH, Wei LN.SourceDepartment of Pharmacology, University of Minnesota Medical School, Minneapolis, MN 55455, USA. Electronic address: ywagley@umn.edu.
Biochimica et biophysica acta.Biochim Biophys Acta.2013 Jun;1833(6):1476-88. doi: 10.1016/j.bbamcr.2013.02.017. Epub 2013 Feb 26.
Despite its potential side effects of addiction, tolerance and withdrawal symptoms, morphine is widely used for reducing moderate and severe pain. Previous studies have shown that the analgesic effect of morphine depends on mu opioid receptor (MOR) expression levels, but the regulatory mechanism of
PMID 23485395

Anethum graveloens Flower Extracts Inhibited a Lipopolysaccharide-Induced Inflammatory Response by Blocking iNOS Expression and NF-κB Activity in Macrophages

KIM Yong-Jae,SHIN Yusu,LEE Kwang Ho,KIM Tack-Joong
Bioscience, biotechnology, and biochemistry 76(6), 1122-1127, 2012-06-23
… In addition, AGF decreased the LPS-induced phosphorylation of mitogen-activated protein kinases in LPS-stimulated RAW 264.7 cells. …
NAID 10030817988

Activation of p38 Mitogen-Activated Protein Kinase Is Inhibited by Hyaluronan via Intercellular Adhesion Molecule-1 in Articular Chondrocytes Stimulated With Type ？ Collagen Peptide

YASUDA Tadashi
Journal of pharmacological sciences 118(1), 25-32, 2012-01-20
… This study examined the activation of p38 mitogen-activated protein kinase with matrix metalloproteinase-13 (MMP-13) production by a synthetic peptide derived from type II collagen (CB12-II) and its inhibition by high molecular weight hyaluronan (HA) in chondrocytes. … The antibody (20 <I>μ</I>g/ml) to intercellular adhesion molecule-1 (ICAM-1), which has been recognized as a receptor of HA on chondrocytes, reversed the HA effect on CB12-II action. …
NAID 10030454028