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- 1. 遺伝的変異の概要 overview of genetic variation
- 2. 分子遺伝学の原理 principles of molecular genetics
- 3. 遺伝性疾患の基本原則 basic principles of genetic disease
English Journal
- A Role for Non-B DNA Forming Sequences in Mediating Micro-Lesions Causing Human Inherited Disease.
- Kamat MA1,2, Bacolla A3, Cooper DN3, Chuzhanova N1.
- Human mutation.Hum Mutat.2015 Oct 15. doi: 10.1002/humu.22917. [Epub ahead of print]
- Missense/nonsense mutations and micro-deletions/micro-insertions (<21bp) represent ∼76% of all mutations causing human inherited disease, and their occurrence has been associated with sequence motifs (direct, inverted and mirror repeats; G-quartets) capable of adopting non-B DNA structures. We
- PMID 26466920
- Comparative analysis of two 16S rRNA gene-based PCR primer sets provides insight into the diversity distribution patterns of anammox bacteria in different environments.
- Wang S1, Hong Y, Wu J, Xu XR, Bin L, Pan Y, Guan F, Wen J.
- Applied microbiology and biotechnology.Appl Microbiol Biotechnol.2015 Oct;99(19):8163-76. doi: 10.1007/s00253-015-6814-8. Epub 2015 Aug 1.
- Due to the high divergence among 16S rRNA genes of anammox bacteria, different diversity pattern of the community could be resulted from using different primer set. In this study, the efficiencies and specificities of two commonly used sets, Amx368F/Amx820R and Brod541F/Amx820R, were evaluated by ex
- PMID 26231134
- Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda.
- Burak MJ, Guja KE, Garcia-Diaz M.
- Nucleic acids research.Nucleic Acids Res.2015 Sep 18;43(16):8089-99. doi: 10.1093/nar/gkv760. Epub 2015 Jul 28.
- 8-Oxo-7,8,-dihydro-2'-deoxyguanosine triphosphate (8-oxo-dGTP) is a major product of oxidative damage in the nucleotide pool. It is capable of mispairing with adenosine (dA), resulting in futile, mutagenic cycles of base excision repair. Therefore, it is critical that DNA polymerases discriminate ag
- PMID 26220180
Japanese Journal
- Repetitive sequences in the lamprey mitochondrial DNA control region and speciation of Lethenteron
- Okada Kazunori,Yamazaki Yuji,Yokobori Shinichi,Wada Hiroshi,和田 洋
- Gene : an international journal focusing on gene cloning and gene structure and function 1-2(465), 45-52, 2010-10-00
- … Detailed analyses of the sequences of the repeats allowed us to deduce that slipped-strand mispairing during DNA replication, accompanied by a high rate of substitutions and indels, was primarily responsible for the variation in the repeats. …
- NAID 120002463167
- アポトーシス誘導経路の分子遺伝学的アプローチ
- 日高 真純
- 福岡歯科大学学会雑誌 35(4), 133-142, 2009-12-30
- … There are two distinct types of DNA lesions that induce apoptosis: modified bases that cause base mispairing and bulky DNA lesions that block DNA replication. …
- NAID 110007521145
- Extreme androgen resistance in a kindred with a novel insertion/deletion mutation in exon 5 of the androgen receptor gene
- Vilchis Felipe,Ramos Luis,Kofman-Alfaro Susana [他],ZENTENO Juan Carlos,MENDEZ Juan Pablo,CHAVEZ Bertha
- Journal of human genetics 48(7), 346-351, 2003-07-01
- NAID 10011595148
Related Links
- mispairing (1) A popular term for the improper alignment of two nucleic acids. (2) Mismatching of nucleotides or noncomplementary pairing of DNA strands that ... These amplicons generate some cross-hybridized products with a ...
- mispairing [mis′per·iŋ] (cell and molecular biology) Pairing of a nucleotide in one chain of a deoxyribonucleic acid molecule that is not complementary to ... Capsule phase variation in Neisseria meningitidis serogroup B by slipped ...
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★リンクテーブル★
| リンク元 | 「不対合」「mispair」「desynapsis」「desynaptic」「誤対合」 |
「不対合」
- 英
- (DNA)mispair、mispairing、(神経)desynapsis、desynaptic
- 関
- 誤対合、ミスペア、不対合形成
「mispair」
「desynapsis」
- n.
「desynaptic」
- 不対合の
「誤対合」
- 英
- mispairing
- 関
- 不対合