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1. 虚血後（虚血性）の急性尿細管壊死の発症および病因 pathogenesis and etiology of postischemic ischemic acute tubular necrosis
2. 巣状分節性糸球体硬化症の疫学、分類、および病因 epidemiology classification and pathogenesis of focal segmental glomerulosclerosis

Protein prenylation in islet β-cell function in health and diabetes: Putting the pieces of the puzzle together.

Kowluru A1, Kowluru RA2.
Biochemical pharmacology.Biochem Pharmacol.2015 Dec 1;98(3):363-70. doi: 10.1016/j.bcp.2015.07.004. Epub 2015 Jul 26.
Post-translational prenylation involves incorporation of 15-(farnesyl) or 20-(geranylgeranyl) carbon derivatives of mevalonic acid into highly conserved C-terminal cysteines of proteins. The farnesyl transferase (FTase) and the geranylgeranyl transferase (GGTase) mediate incorporation of farnesyl an
PMID 26215874

MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis.

MacNair L1, Xiao S2, Miletic D2, Ghani M2, Julien JP3, Keith J4, Zinman L5, Rogaeva E2, Robertson J6.
Brain : a journal of neurology.Brain.2015 Nov 2. pii: awv308. [Epub ahead of print]
Tar DNA-binding protein 43 (TDP-43) is an RNA-binding protein normally localized to the nucleus of cells, where it elicits functions related to RNA metabolism such as transcriptional regulation and alternative splicing. In amyotrophic lateral sclerosis, TDP-43 is mislocalized from the nucleus to the
PMID 26525917

Stepicheva NA1, Song JL2.
Development (Cambridge, England).Development.2015 Nov 1;142(21):3769-80. doi: 10.1242/dev.127969. Epub 2015 Sep 23.
MicroRNAs (miRNAs) are small non-coding RNAs that repress the translation and reduce the stability of target mRNAs in animal cells. microRNA-31 (miR-31) is known to play a role in cancer, bone formation and lymphatic development. However, studies to understand the function of miR-31 in embryogenesis
PMID 26400092

Yamada Yuki,Kawabe Takahiro,Miura Kayo
Neuroscience Letters 531(2), 96-98, 2012-11-30
… The results indicated that the observers significantly mislocalized the target 1.61' on average toward the location of their own name. …
NAID 120004951633

伊東大介
臨床神経学 52(11), 1221-1223, 2012
… TDP-43 and FUS are normally localized in the nucleus, in sites affected by ALS and FTLD-U, but both are mislocalized to the cytoplasm and form cytoplasmic inclusions. …
NAID 130004505112