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English Journal

Intrinsic cardiomyopathy in Marfan syndrome: results from in- and ex-vivo studies of the Fbn1C1039G/+ model and longitudinal findings in humans.

Campens L1, Renard M1, Trachet B2, Segers P2, Muino Mosquera L1, De Sutter J3, Sakai L4, De Paepe A1, De Backer J1.
Pediatric research.Pediatr Res.2015 Jun 4. doi: 10.1038/pr.2015.110. [Epub ahead of print]
BACKGROUND: Mild intrinsic cardiomyopathy in patients with Marfan syndrome (MFS) has consistently been evidenced by independent research groups. So far, little is known about the long-term evolution and pathophysiology of this finding.METHODS: To gain more insights into the pathophysiology of MFS-re
PMID 26042521

Microfibrillar-associated protein 4 modulates airway smooth muscle cell phenotype in experimental asthma.

Pilecki B1, Schlosser A1, Wulf-Johansson H1, Trian T2, Moeller JB1, Marcussen N3, Aguilar-Pimentel JA4, de Angelis MH5, Vestbo J6, Berger P7, Holmskov U1, Sorensen GL1.
Thorax.Thorax.2015 Jun 2. pii: thoraxjnl-2014-206609. doi: 10.1136/thoraxjnl-2014-206609. [Epub ahead of print]
BACKGROUND: Recently, several proteins of the extracellular matrix have been characterised as active contributors to allergic airway disease. Microfibrillar-associated protein 4 (MFAP4) is an extracellular matrix protein abundant in the lung, whose biological functions remain poorly understood. In t
PMID 26038533

Characterization of spontaneous air space enlargement in mice lacking microfibrillar-associated protein 4.

Holm AT1, Wulf-Johansson H1, Hvidsten S2, Jorgensen PT1, Schlosser A1, Pilecki B1, Ormhøj M1, Moeller JB1, Johannsen C2, Baun C2, Andersen T2, Schneider JP3, Hegermann J3, Ochs M3, Götz AA4, Schulz H5, de Angelis MH6, Vestbo J7, Holmskov U1, Sorensen GL8.
American journal of physiology. Lung cellular and molecular physiology.Am J Physiol Lung Cell Mol Physiol.2015 Jun 1;308(11):L1114-24. doi: 10.1152/ajplung.00351.2014. Epub 2015 Apr 10.
Microfibrillar-associated protein 4 (MFAP4) is localized to elastic fibers in blood vessels and the interalveolar septa of the lungs and is further present in bronchoalveolar lavage. Mfap4 has been previously suggested to be involved in elastogenesis in the lung. We tested this prediction and aimed
PMID 26033354

Efficacy and Safety of Preoperative Portal Vein Embolization with Microfibrillar Collagen for Hepatobiliary Malignancy

Shibutani Koichi,Tsushima Fumiyasu,Kakehata Shinya,Miura Hiroyuki,Ono Shuichi,Seino Hiroko,Kakuta Akihisa,Tokuda Toshihide,Toyoki Yoshikazu,Hakamada Kenichi,Takai Yoshihiro
弘前医学 64(1), 1-14, 2013-05-31
… Purpose: To evaluate the clinical efficacy and safety of preoperative percutaneous transhepatic portal vein embolization（PVE） with an ipsilateral approach, using microfibrillar collagen（MFC） as an embolic material for carcinomas of the biliary tract and liver metastases of colorectal carcinoma. …
NAID 120005303550

Efficacy and Safety of Preoperative Portal Vein Embolization with Microfibrillar Collagen for Hepatobiliary Malignancy

Shibutani Koichi,Tsushima Fumiyasu,Kakehata Shinya,Miura Hiroyuki,Ono Shuichi,Seino Hiroko,Kakuta Akihisa,Tokuda Toshihide,Toyoki Yoshikazu,Hakamada Kenichi,Takai Yoshihiro
弘前醫學 64(1), 1-14, 2013
NAID 110009614109