English Journal
- Crystal structure of Plasmodium falciparum adenosine deaminase reveals a novel binding pocket for inosine.
- Jaruwat A, Riangrungroj P, Ubonprasert S, Sae-Ueng U, Kuaprasert B, Yuthavong Y, Leartsakulpanich U, Chitnumsub P.
- Archives of biochemistry and biophysics. 2019 Apr;667()6-13.
- Plasmodium falciparum (Pf), a malarial pathogen, can only synthesize purine nucleotides employing a salvage pathway because it lacks de novo biosynthesis. Adenosine deaminase (ADA), one of the three purine salvage enzymes, catalyzes the irreversible hydrolytic deamination of adenosine to inosine, wh
- PMID 31002765
- PMA treated THP-1-derived-IL-6 promotes EMT of SW48 through STAT3/ERK-dependent activation of Wnt/β-catenin signaling pathway.
- Gao S, Hu J, Wu X, Liang Z.
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2018 Dec;108()618-624.
- Colon cancer is one of the most common digestive malignant tumors that leads to high mortality worldwide, and metastasis is the primary cause of cancer-related death. It is well accepted that the epithelial-mesenchymal transition (EMT) plays a key role in the process of metastasis. As a cytokine tha
- PMID 30243096
- Three Faces of Mercaptopurine Cytotoxicity In Vitro: Methylation, Nucleotide Homeostasis, and Deoxythioguanosine in DNA.
- Coulthard SA, McGarrity S, Sahota K, Berry P, Redfern CPF.
- Drug metabolism and disposition: the biological fate of chemicals. 2018 08;46(8)1191-1199.
- Mercaptopurine (MP) is a cytotoxic thiopurine important for the treatment of cancer and autoimmune diseases. MP and other thiopurine drugs undergo extensive intracellular metabolism, but the mechanisms of action are poorly characterized. In particular, it is unknown how different metabolites contrib
- PMID 29884651
Japanese Journal
- Studies of Nucleosides and Nucleotides. LXXXI. Synthesis and Characterization of 8-Methyladenosine
- Chemical & pharmaceutical bulletin 25(10), 2702-2707, 1977-10-25
- NAID 110003622250
- Studies of nucleosides and nucleotides. LXXXI. Synthesis and characterization of 8-methyladenosine.
- Chemical and Pharmaceutical Bulletin 25(10), 2702-2707, 1977
- NAID 130003767843
- Synthesis of 2-Methoxyinosine and Its 5'-Phosphate
- Chemical & pharmaceutical bulletin 17(12), 2581-2585, 1969-12-25
- NAID 110003654559
Related Links
- 6-Methylthioinosine | C11H14N4O4S | CID 237358 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. ...
- 6-MeTIMP：6-methylthioinosine monophosphate，6-MeTITP：6-methylthioinosine triphosphate，6-TXMP：6-thioxanthosine 5ʼ-monophosphate，6-TGN：6-thio-guanine nucleotide, and 6-MeTGN：6-methylthioguanine nucleotide. ...
- 5'-Deoxy-5'-methylthioinosine; S-Methyl-5'-thioinosine Formula C11H14N4O4S Exact mass 298.0736 Mol weight 298.3183 Structure Reaction R09660 R09668 Pathway map00270 Cysteine and methionine metabolism map01100 ...
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