メチルグルカミン
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/06/07 20:24:14」(JST)
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Meglumine
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Names |
Systematic IUPAC name
(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentol
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Other names
Methylglucamine; N-Methylglucamine; 1-Deoxy-1-(methylamino)-D-glucitol; 1-Deoxy-1-methylaminosorbitol; N-Methylsorbitylamine; Meglumin
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Identifiers |
CAS Number
|
6284-40-8 Y |
ChEBI |
CHEBI:59732 N |
ChEMBL |
ChEMBL1200570 N |
ChemSpider |
8249 N |
Jmol 3D model |
Interactive image |
PubChem |
8567 |
UNII |
6HG8UB2MUY N |
InChI
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InChI=1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1 N
Key: MBBZMMPHUWSWHV-BDVNFPICSA-N N
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SMILES
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O[C@H]([C@@H](O)CNC)[C@H](O)[C@H](O)CO
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Properties |
Chemical formula
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C7H17NO5 |
Molar mass |
195.22 g·mol−1 |
Appearance |
White crystals |
log P |
−2.509 |
Acidity (pKa) |
9.52 |
Basicity (pKb) |
0.526 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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N verify (what is YN ?) |
Infobox references |
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Meglumine is an amino sugar derived from sorbitol. It is often used as an excipient in pharmaceuticals and in conjunction with iodinated compounds in contrast media such as diatrizoate meglumine and iodipamide meglumine.[1]
See also
- Flunixin meglumine
- Meglumine antimoniate
References
- ^ Meglumine, chemicalland21.com
UpToDate Contents
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English Journal
- Effects of tafamidis treatment on transthyretin (TTR) stabilization, efficacy, and safety in Japanese patients with familial amyloid polyneuropathy (TTR-FAP) with Val30Met and non-Varl30Met: A phase III, open-label study.
- Yukio A1, Yoshiki S2, Konen O3, Taro Y4, Mitsuharu U5, Yohei M6, Hiroshi M7, Katsuyuki M8, Makoto O9, Ami T10, Shû-Ichi I11.
- Journal of the neurological sciences.J Neurol Sci.2016 Mar 15;362:266-71. doi: 10.1016/j.jns.2016.01.046. Epub 2016 Jan 22.
- INTRODUCTION: The efficacy and safety of tafamidis in transthyretin (TTR) familial amyloid polyneuropathy (TTR-FAP) were evaluated in this open-label study.METHODS: Japanese TTR-FAP patients (n=10; mean age 60.1years) received tafamidis meglumine (20mg daily; median treatment duration 713.5days). Th
- PMID 26944161
- In vivo and in vitro effects of pentavalent antimony on mouse liver cytochrome P450s.
- Coelho DR1, De-Oliveira A1, Parente T1, Leal BS1, das Chagas LF1, Oliveira TN1, Saint'Pierre TD2, Paumgartten F3.
- Human & experimental toxicology.Hum Exp Toxicol.2016 Mar 4. pii: 0960327116637110. [Epub ahead of print]
- Pentavalent antimonial (Sb5+) drugs such as meglumine antimoniate (MA) are the mainstay treatment of leishmaniases in developing countries. The effects of these compounds on drug-metabolizing enzymes have not been characterized and their potential pharmacokinetic interactions with other drugs are th
- PMID 26944940
- Re: The Benefits of High Relaxivity for Brain Tumor Imaging: Results of a Multicenter Intraindividual Crossover Comparison of Gadobenate Dimeglumine with Gadoterate Meglumine (The BENEFIT Study).
- Lancelot E1, Piednoir B1, Desché P1.
- AJNR. American journal of neuroradiology.AJNR Am J Neuroradiol.2016 Mar;37(3):E20-1. doi: 10.3174/ajnr.A4646. Epub 2016 Jan 14.
- PMID 26767706
Japanese Journal
- Proton-Coupled Organic Cation Antiporter-Mediated Uptake of Apomorphine Enantiomers in Human Brain Capillary Endothelial Cell Line hCMEC/D3
- ナイロン繊維にグラフト重合したポリグリシジルメタクリレートへのN-メチルグルカミン固定反応に適する溶媒の選択
Related Links
- Meglumin;MeguMine;MEGLUMINE;Methylglucamin;N-Methyl-D-Glu;MEGLUMINE, USP;MegluMine (AS);Methylglucamine;N-METHYLGLUCAMINE;Methylglucamine,99% CBNumber: CB6411710 分子式: C7H17NO5 分子量: ...
- forum Join the Word of the Day Mailing List For webmasters TheFreeDictionary Google Bing? Word / Article Starts with Ends with Text ... methylglucamine /meth·yl·glu·ca·mine/ (-gloo´kah-mēn) meglumine. meth·yl·glu·ca·mine (meth ...
Related Pictures
★リンクテーブル★
[★]
- 英
- meglumine
- ラ
- megluminum
- 同
- メチルグルカミン methylglucamine
- 商
- アトルバスタチン、ウログラフイン、ガストログラフイン、ガドペンテト酸メグルミン、コンレイ、ビリスコピン、プロイメンド、マグネスコープ、マグネビスト
参考
- http://ja.wikipedia.org/wiki/%E3%83%A1%E3%82%B0%E3%83%AB%E3%83%9F%E3%83%B3
[★]
- 英
- methylglucamine
- 関
- メグルミン