メタロエキソペプチダーゼ
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/16 14:06:09」(JST)
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A metalloexopeptidase is a type of enzyme that acts as a metalloproteinase exopeptidase.
The term "metallocarboxypeptidase" is sometimes used to describe a metalloexopeptidase carboxypeptidase.
External links
- Metalloexopeptidase at the US National Library of Medicine Medical Subject Headings (MeSH)
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Hydrolase: proteases (EC 3.4)
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| 3.4.11-19: Exopeptidase |
| 3.4.11 |
- Aminopeptidase
- Alanine
- Arginyl
- Aspartyl
- Cystinyl
- Leucyl
- Glutamyl
- Methionyl
- O
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| 3.4.13 |
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| 3.4.14 |
- Dipeptidyl peptidase
- Cathepsin C
- Dipeptidyl peptidase-4
- Tripeptidyl peptidase
- Tripeptidyl peptidase I
- Tripeptidyl peptidase II
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| 3.4.15 |
- Angiotensin-converting enzyme
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| 3.4.16 |
- Serine type carboxypeptidases: Cathepsin A
- DD-transpeptidase
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| 3.4.17 |
- Metalloexopeptidases
- Carboxypeptidase
- A
- A2
- B
- C
- E
- Glutamate II
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| Other/ungrouped |
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| 3.4.21-24: Endopeptidase |
- Serine proteases
- Cysteine protease
- Aspartic acid protease
- Metalloendopeptidases
- PRSS8
- Other/ungrouped: Amyloid precursor protein secretase
- Alpha secretase
- Beta-secretase 1
- Beta-secretase 2
- Gamma secretase
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| 3.4.99: Unknown |
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- Biochemistry overview
- Enzymes overview
- By EC number: 1.1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- 10
- 11
- 13
- 14
- 15-18
- 2.1
- 3.1
- 4.1
- 5.1
- 6.1-3
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English Journal
- Cloning and characterization of canine prostate-specific membrane antigen.
- Schmidt S, Fracasso G, Colombatti M, Naim HY.SourceDepartment of Physiological Chemistry, University of Veterinary Medicine Hannover, Hannover, Germany.
- The Prostate.Prostate.2013 May;73(6):642-50. doi: 10.1002/pros.22605. Epub 2013 Jan 28.
- BACKGROUND: Prostate-specific membrane antigen (PSMA) is a promising biomarker in the diagnosis of prostate cancer and a potential target for antibody-based therapeutic strategies. We isolated the canine PSMA cDNA and investigated the cellular and biochemical characteristics of the recombinant prote
- PMID 23359458
- Association of glutamate carboxypeptidase II (GCPII) haplotypes with breast and prostate cancer risk.
- Divyya S, Naushad SM, Addlagatta A, Murthy PV, Reddy ChR, Digumarti RR, Gottumukkala SR, Subbarao SA, Kutala VK.SourceDepartment of Clinical Pharmacology & Therapeutics, Nizam's Institute of Medical Sciences, India.
- Gene.Gene.2013 Mar 1;516(1):76-81. doi: 10.1016/j.gene.2012.11.047. Epub 2012 Dec 22.
- In view of the pivotal role of glutamate carboxypeptidase II (GCPII) in carcinogenesis, its expression as prostate specific membrane antigen (PSMA) and folate hydrolase (FOLH1) may be influenced by its haplotypes, contributing to the etiology of prostate and breast cancer. To test this hypothesis, b
- PMID 23266799
- Network modeling reveals steps in angiotensin peptide processing.
- Schwacke JH, Spainhour JC, Ierardi JL, Chaves JM, Arthur JM, Janech MG, Velez JC.SourceMedical University of South Carolina, Charleston, SC 29425, USA.
- Hypertension.Hypertension.2013 Mar;61(3):690-700. doi: 10.1161/HYPERTENSIONAHA.111.00318. Epub 2013 Jan 2.
- New insights into the intrarenal renin-angiotensin (Ang) system have modified our traditional view of the system. However, many finer details of this network of peptides and associated peptidases remain unclear. We hypothesized that a computational systems biology approach, applied to peptidomic dat
- PMID 23283355
Japanese Journal
- Enhanced accessibility of peptide substrate toward a membrane-bound metalloexopeptidase by supramolecular structure of polyrotaxane
Related Links
- Neil D. Rawlings, Alan J. Barrett, in Handbook of Proteolytic Enzymes (Third Edition), 2013 Clan MC Clan MC contains the metallocarboxypeptidases of in which there is one catalytic zinc ion tetrahedrally coordinated by a water ...
- A metalloexopeptidase is a type of enzyme that acts as a metalloproteinase exopeptidase. These enzymes have a catalytic mechanism involving a metal, often zinc. They function in molecular biology as agents that cut the terminal ...