WordNet
- cover with metal
PrepTutorEJDIC
- 〈C〉(個々の)『金属』;〈U〉(材料としての)金属 / 〈U〉合金(真ちゅう,真銅など) / 〈U〉気性,気質 / 〈U〉《英》(舗装用・鉄道用の)砕石 / …‘に'金属をかぶせる / 《英》〈道路〉‘に'砕石を敷く
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- 1. カルバペネマーゼ carbapenemases
- 2. 高血圧のマネージメントにおけるバゾペプチターゼ阻害剤 vasopeptidase inhibition in the management of hypertension
- 3. Chapter 6D：ナトリウム利尿ペプチド chapter 6d natriuretic peptides
- 4. 先天性乳児ネフローゼ症候群 congenital and infantile nephrotic syndrome
- 5. 慢性収縮期心不全に対する、効果が実証されていない治療 unproven therapies for chronic systolic heart failure
English Journal
- Neutral endopeptidase (CD10) is abundantly expressed in the epididymis and localized to a distinct population of epithelial cells--its relevance for CNP degradation.
- Thong A, Müller D, Feuerstacke C, Mietens A, Stammler A, Middendorff R.Author information Institute of Anatomy and Cell Biology, Justus-Liebig-University Giessen, 35385 Giessen, Germany.AbstractNeutral endopeptidase (NEP, metallo-endopeptidase EC 3.4.24.11; enkephalinase, neprilysin, CD10, CALLA) represents a major regulator of bioactivity of natriuretic peptides. C-type natriuretic peptide (CNP) is present in high levels in epididymis and seminal plasma. However, detailed expression pattern and CNP-related function of NEP in the epididymis are unknown. Comparison of NEP protein levels in various organs revealed an extremely high expression in human and mouse epididymis. NEP was localized exclusively to apical (luminal) parts of epithelial cells. In man, strong NEP-immunoreactivity was associated with epithelia of efferent ducts and the epididymal duct including stereocilia. Segment-by-segment analysis in mouse revealed a distinct distribution along the epididymal duct. We also found the CNP receptor guanylyl cyclase B (GC-B) in epithelial cells of the epididymal duct. Two different NEP inhibitors decreased CNP degradation and increased CNP/GC-B-induced cGMP production by epididymal membranes, suggesting a functional involvement of NEP. Data indicate an important, previously neglected, role of NEP for regulation of luminal factors in the epididymis and suggest a novel role for CNP/GC-B in the epididymal epithelium, presumably in context of local water balance.
- Molecular and cellular endocrinology.Mol Cell Endocrinol.2014 Jan 25;382(1):234-43. doi: 10.1016/j.mce.2013.09.027. Epub 2013 Oct 4.
- Neutral endopeptidase (NEP, metallo-endopeptidase EC 3.4.24.11; enkephalinase, neprilysin, CD10, CALLA) represents a major regulator of bioactivity of natriuretic peptides. C-type natriuretic peptide (CNP) is present in high levels in epididymis and seminal plasma. However, detailed expression patte
- PMID 24099862
- Analysis of differentially expressed genes in various stages of Duchenne muscular dystrophy by using a network view.
- Wang D, Wang ZJ, Song XX, Pu LH, Li X, Wang Y.Author information Department of Neurology, Xi'an Children's Hospital, Xi'an, Shaanxi, China wangdong6928@yahoo.cn.AbstractDuchenne muscular dystrophy (DMD), which is caused by mutations in the X-linked dystrophin gene, is a severe and progressive neuromuscular disease with no available cure. By integrating 2 microarray datasets from the Gene Expression Omnibus, we identified differentially expressed genes in 2 stages of DMD and systematically explored their potential disease-related mechanisms using a network view. Twenty differentially expressed genes were detected in various stages of DMD. According to the network with dystrophin as its center, none of the 20 proteins interacts with dystrophin directly. IQ motif-containing GTPase-activating protein 1 was found in the 2nd-level neighbors with a degree of 21. Microtubule-associated protein tau, membrane metallo-endopeptidase, interleukin 13 receptor alpha 1, and multiple epidermal growth factor-like domains 6 were found in the 3rd-level neighbors. These identifications require further investigation, as this report is the first of possible associations between DMD and these proteins. Analysis of differentially expressed genes through this network view may provide important information for further exploration of underlying mechanisms of DMD.
- Genetics and molecular research : GMR.Genet Mol Res.2013 Oct 10;12(4):4480-8. doi: 10.4238/2013.October.10.13.
- Duchenne muscular dystrophy (DMD), which is caused by mutations in the X-linked dystrophin gene, is a severe and progressive neuromuscular disease with no available cure. By integrating 2 microarray datasets from the Gene Expression Omnibus, we identified differentially expressed genes in 2 stages o
- PMID 24222227
- [Pathological and immunohistochemical analyses of 32 cases of nephrogenic adenoma].
- Shen Q, Sun LH, Wang JH, Liu LB, He Q, Jin J.Author information Department of Urology, Peking University First Hospital; Institute of Urology, Peking University; National Urological Cancer Center, Beijing 100034, China.AbstractOBJECTIVE: To observe clinical and pathological features of nephrogenic adenoma (NA), and to find some useful immunohistochemical markers for its diagnosis.
- Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences.Beijing Da Xue Xue Bao.2013 Aug 18;45(4):522-6.
- OBJECTIVE: To observe clinical and pathological features of nephrogenic adenoma (NA), and to find some useful immunohistochemical markers for its diagnosis.METHODS: The clinical features of 32 NA patients were obtained. Each case underwent microscopic observation and immumohistochemical staining. Th
- PMID 23939154
Japanese Journal
- Effect of Chronic Topical Exposure to Low-Dose Noxious Chemicals and Stress on Skin Sensitivity in Mice
- Journal of occupational health 49(6), 431-442, 2007-11
- NAID 110006545915
- Effect of Chronic Topical Exposure to Low-Dose Noxious Chemicals and Stress on Skin Sensitivity in Mice
- Journal of Occupational Health 49(6), 431-442, 2007
- NAID 130004447404
- 内在性エンドペプチダーゼ (EP) およびトランスグルタミナーゼ (TGase) の制御がコイ肉の坐り特性に及ぼす影響
- 日本水産学会誌 66(4), 719-725, 2000-07-15
- NAID 110003145079
Related Links
- Gene ID: 17380, updated on 8-Aug-2016 Summary Other designations atriopeptidase, common acute lymphoblastic leukemia antigen, enkephalinase, neutral endopeptidase 24.11, skin fibroblast elastase GeneRIFs: Gene References ...
- ... common acute lymphocytic leukemia antigen, membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10), membrane metallo-endopeptidase variant 1, membrane metallo-endopeptidase variant 2, ...
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★リンクテーブル★
| リンク元 | 「metalloendopeptidase」「金属エンドペプチダーゼ」「メタロエンドペプチダーゼ」 |
| 関連記事 | 「metal」「metallo」 |
「metalloendopeptidase」
「金属エンドペプチダーゼ」
「メタロエンドペプチダーゼ」
「metal」
- n.
- adj.
- 金属の