mammosomatotroph

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Pituitary adenoma with gangliocytic component: report of 5 cases with focus on immunoprofile of gangliocytic component.

Balci S1, Saglam A, Oruckaptan H, Erbas T, Soylemezoglu F.
Pituitary.Pituitary.2015 Feb;18(1):23-30. doi: 10.1007/s11102-013-0551-8.
INTRODUCTION: Pituitary adenomas with gangliocytic component are rare tumors of the sellar region that are composed of pituitary adenoma cells and a ganglion cell component. Their histogenesis and hence nosology is not yet resolved because of the small number of cases reported and lack of large seri
PMID 24430434

Metabolic glucose status and pituitary pathology portend therapeutic outcomes in acromegaly.

Cheng S1, Al-Agha R, Araujo PB, Serri O, L Asa S, Ezzat S.
PloS one.PLoS One.2013 Sep 9;8(9):e73543. doi: 10.1371/journal.pone.0073543. eCollection 2013.
INTRODUCTION: Acromegaly is frequently associated with impaired glucose tolerance and/or diabetes. To evaluate the relationship between glucose metabolism and acromegaly disease, we evaluated 269 consecutive patients from two referral centres.METHODS: Clinical presentation, pituitary tumor size and
PMID 24039977

Discordant growth hormone and IGF-1 levels post pituitary surgery in patients with acromegaly naïve to medical therapy and radiation: what to follow, GH or IGF-1 values?

Brzana JA1, Yedinak CG, Delashaw JB, Gultelkin HS, Cook D, Fleseriu M.
Pituitary.Pituitary.2012 Dec;15(4):562-70. doi: 10.1007/s11102-011-0369-1.
New criteria that define acromegaly remission are more stringent: normal (age/sex-adjusted) insulin-like growth factor type 1 (IGF-1), growth hormone (GH) random (GHr) <1 μg/L, and a GH nadir (GHn) during oral glucose tolerance test (OGTT) of <0.4 μg/L. Discordance between GH and IGF-1 value
PMID 22183781

佐野壽昭,堀口英久,山田正三
脳神経外科ジャーナル 14(1), 10-17, 2005-01-20
下垂体腺腫の枠組みについて著者らは,1)GH-PRL-TSH細胞グループ,ACTH細胞グループ,ゴナドトロピン細胞グループに大別され,2)各グループの枠を超えた複数のホルモンが1つの腺腫に共存する可能性はきわめて低く,3)各グループにはホルモン過剰症状を呈する腺腫とそれを欠く腺腫とがある,と考えている.2004年秋に刊行される予定の新WHO分類はKovacsらの病理組織学的分類を基盤にしており,分 …
NAID 110003813973

30-II-13 ラットmammosomatotrophの局在とその意義(内分泌,一般口演,第44回日本組織細胞化学会第35回日本臨床電子顕微鏡学会合同学術集会)

Induction of mammotroph development by a combination of epidermal growth factor, insulin, and estradiol-17β in rat pituitary tumor GH3 cells

Kakeya Tomoshi,Takeuchi Sakae,Takahashi Sumio
Zoological science 19(7), 789-795, 2002-07-25
Several reports have indicated that prolactin-secreting cells (PRL cells) are generated from growth hormone-secreting cells (GH cells). We have shown that treatment with a combination of epidermal gro …
NAID 110003372783