関: gluconate、gluconic acid、zinc gluconate

WordNet

a light silver-white ductile bivalent metallic element; in pure form it burns with brilliant white flame; occurs naturally only in combination (as in magnesite and dolomite and carnallite and spinel and olivine) (同)Mg, atomic number 12

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マグネシウム(金属元素;化学記号は『Mg』)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/06/14 22:20:31」(JST)

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Magnesium gluconate is a compound with formula MgC₁₂H₂₂O₁₄. It is the magnesium salt of gluconic acid.

According to scientific research, magnesium gluconate shows the highest level of bioavailability of any magnesium salt and is recommended as the optimal salt for human supplementation although of the 10 salts studied, all increased Magnesium levels significantly.^[1]

It has E number "E580".

Use in Medicine

There are data on the pharmacological properties of magnesium gluconate. Gluconic acid is the initial substrate for the reactions of pentose phosphate path of oxidation of glucose, so it was suggested that it may affect the energy metabolism of mitochondria.^{[citation needed]} In Ukraine, magnesium gluconate, together with potassium gluconate in the drug Rhythmocor is used to treat heart disease. Pilot studies have shown efficacy in various cardiac arrhythmia.^{[citation needed]} Whether these effects are from the influence of gluconic acid on the metabolism of the heart or from the influence of magnesium and potassium on osmotic pressure is unknown.

References

^ Coudray, C; Rambeau, M; Feillet-Coudray, C; Gueux, E; Tressol, JC; Mazur, A; Rayssiguier, Y (2005). "Study of magnesium bioavailability from ten organic and inorganic Mg salts in Mg-depleted rats using a stable isotope approach". Magnesium research : official organ of the International Society for the Development of Research on Magnesium 18 (4): 215–23. PMID 16548135.

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English Journal

High yield production of d-xylonic acid from d-xylose using engineered Escherichia coli.

Liu H, Valdehuesa KN, Nisola GM, Ramos KR, Chung WJ.SourceEnergy and Environment Fusion Technology Center (E(2)FTC), Myongji University, Yongin City, Gyeonggi Province 449-728, South Korea.
Bioresource technology.Bioresour Technol.2012 Jul;115:244-8. Epub 2011 Aug 22.
An engineered Escherichia coli was constructed to produce d-xylonic acid, one of the top 30 high-value chemicals identified by US Department of Energy. The native pathway for d-xylose catabolism in E. coli W3110 was blocked by disrupting xylose isomerase (XI) and xylulose kinase (XK) genes. The nati
PMID 21917451

CIEL*a*b* parameters of white dehydrated grapes as quality markers according to chemical composition, volatile profile and mechanical properties.

Rolle L, Giordano M, Giacosa S, Vincenzi S, Río Segade S, Torchio F, Perrone B, Gerbi V.SourceUniversity of Turin, DIVAPRA - Food Technology sector, Via L. da Vinci 44, 10095 Grugliasco (TO), Italy.
Analytica chimica acta.Anal Chim Acta.2012 Jun 30;732:105-13. Epub 2011 Nov 28.
In the oenological sector, the withering process is of particular importance in the production of dry and sweet dessert wines due to the total or partial use of overripe and/or dehydrated grapes. This complex process leads to several changes in the chemical-physical characteristics of white grape be
PMID 22688041

Japanese Journal

Method for Estimating Quantity of Non-Hydrated Cement in a Cement Recycling System

Atarashi Daiki,Kamio Tetsuji,Aikawa Yutaka,Miyauchi Masahiro,Sakai Etsuo
Journal of Advanced Concrete Technology 13(1), 44-49, 2015
… The objective of this research was to develop a method for the rapid estimation of the quantity of residual cement in sludge water and to control its hydration reaction using sodium gluconate in order to enable the residual cement in sludge water to be effectively utilized. … It is possible to recommence sodium gluconate-controlled cement hydration using magnesium nitrate. …
NAID 130004940160

Goshajinkigan, a Traditional Japanese Medicine, Prevents Oxaliplatin-Induced Acute Peripheral Neuropathy by Suppressing Functional Alteration of TRP Channels in Rat

Mizuno Keita,Kono Toru,Suzuki Yasuyuki [他],Miyagi Chika,Omiya Yuji,Miyano Kanako,Kase Yoshio,Uezono Yasuhito
Journal of Pharmacological Sciences 125(1), 91-98, 2014
… Administration of oxaliplatin increased withdrawal responses from cold stimulation, and GJG or calcium gluconate/magnesium sulfate significantly inhibited the oxaliplatin-induced cold hypersensitivity. …
NAID 130004933173

Efficacy of Goshajinkigan for Peripheral Neurotoxicity of Oxaliplatin in Patients with Advanced or Recurrent Colorectal Cancer

河野透,Mamiya Noriaki,Chisato Naoyuki,Ebisawa Yosiaki,Yamazaki Hirotaka,Watari Jiro,Yamamoto Yasuhiro,Suzuki Shigetaka,Asama Toshiyuki,Kamiya Kazunori
Evidence-based Complementary and Alternative Medicine (2011), 418481-1-418481-8, 2011
… (Group A, n = 11), intravenous supplementation of calcium gluconate and magnesium sulfate (1 g each before and after FOLFOX) (Group B, n = 14), combined GJG and calcium gluconate and magnesium sulfate therapies (Group C, n = 21), or no concomitant therapy (Group D, n = 44). …
NAID 120004461842

「zinc gluconate」

Magnesium gluconate
Names
	IUPAC name Magnesium bis[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate]
Identifiers
CAS Number	3632-91-5
ChEMBL	ChEMBL2107145
ChemSpider	9593457
Jmol 3D model	Interactive image
PubChem	11418570
	InChI InChI=1S/2C6H12O7.Mg/c27-1-2(8)3(9)4(10)5(11)6(12)13;/h22-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1 ;
	SMILES [Mg+2].[O-]C(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[O-]C(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO ;
Properties
Chemical formula	C12H22MgO14
Molar mass	414.60 g·mol−1
Pharmacology
ATC code	A12CC03 (WHO)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references