WordNet

any substance (such as an antibody) or agent that can cause lysis
an essential amino acid found in proteins; occurs especially in gelatin and casein

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Chen Y, Terajima M, Yang Y, Sun L, Ahn YH, Pankova D, Puperi DS, Watanabe T, Kim MP, Blackmon SH, Rodriguez J, Liu H, Behrens C, Wistuba II, Minelli R, Scott KL, Sanchez-Adams J, Guilak F, Pati D, Thilaganathan N, Burns AR, Creighton CJ, Martinez ED, Zal T, Grande-Allen KJ, Yamauchi M, Kurie JM.
The Journal of clinical investigation.J Clin Invest.2015 Feb 9. pii: 74725. doi: 10.1172/JCI74725. [Epub ahead of print]
Epithelial tumor metastasis is preceded by an accumulation of collagen cross-links that heighten stromal stiffness and stimulate the invasive properties of tumor cells. However, the biochemical nature of collagen cross-links in cancer is still unclear. Here, we postulated that epithelial tumorigenes
PMID 25664850

The in Vivo Effect of Prophylactic Subchondral Bone Protection of Osteoarthritic Synovial Membrane in Bone-Specific Ephb4-Overexpressing Mice.

Valverde-Franco G1, Hum D1, Matsuo K2, Lussier B3, Pelletier JP1, Fahmi H1, Kapoor M1, Martel-Pelletier J4.
The American journal of pathology.Am J Pathol.2015 Feb;185(2):335-46. doi: 10.1016/j.ajpath.2014.10.004. Epub 2014 Nov 29.
Osteoarthritis (OA) is characterized by progressive joint destruction, including synovial membrane alteration. EphB4 and its ligand ephrin-B2 were found in vitro to positively affect OA subchondral bone and cartilage. In vivo in an experimental mouse model overexpressing bone-specific Ephb4 (TgEph
PMID 25453723

Skin malformations in a neonatal foal tested homozygous positive for Warmblood Fragile Foal Syndrome.

Monthoux C, de Brot S, Jackson M, Bleul U, Walter J.
BMC veterinary research.BMC Vet Res.2015 Jan 31;11(1):12. [Epub ahead of print]
BackgroundSkin malformations that resembled manifestations of Ehlers-Danlos-Syndrome were described in a variety of domestic animals during the last century as cutis hyperelastica, hyperelastosis cutis, dermatosparaxis, dermal/collagen dysplasia, dermal/cutaneous asthenia or Ehlers-Danlos-like syndr
PMID 25637337

松浦尚志,片渕三千綱,徳富健太郎,佐藤博信
福岡歯科大学学会雑誌 33(3), 133-145, 2007-09-30
… Among extensive posttranslational modifications of collagen, lysine (Lys) hydroxylation is important for physiological and pathophysiological conditions of connective tissues. … The specific Lys residues are catalyzed by three isoforms of lysyl hydroxylase (LH, known as PLOD : procollagen-lysine, 2-oxoglutarate 5-dioxygenase). …
NAID 110006436919

Effects of Dipeptides Having a C-Terminal Lysine on the Cholesterol 7α-Hydroxylase mRNA Level in HepG2 Cells

Morikawa Kensei,Ishikawa Kumiko,Kanamaru Yoshihiro [他],HORI Goro,NAGAOKA Satoshi
Bioscience, biotechnology, and biochemistry 71(3), 821-825, 2007-03-23
… Inducing expression of the cholesterol-catabolizing enzyme cholesterol 7α-hydroxylase (CYP7A1) in the liver can be an effective strategy in preventing hypercholesterolemia and atherosclerosis. … We used HepG2 cells to investigate the effects of 1 mM dipeptides having a C-terminal lysine group on the CYP7A1 mRNA level. …
NAID 10027513099

Pharmacological Characteristics of Rotational Behavior in Hemiparkinsonian Rats Transplanted With Mouse Embryonic Stem Cell-Derived Neurons

Inden Masatoshi,Kim Dohoon,Gu Yuanjin,Kitamura Yoshihisa,Kondo Jun-ichi,Tsuchiya Daiju,Taniguchi Takashi,Shimohama Shun,Akaike Akinori,Sumi Shoichiro,Inoue Kazutomo
Journal of Pharmacological Sciences 96(1), 53-64, 2004
… Apomorphine-induced rotation was significantly reduced by transplantation of neuron-like cells that had differentiated from mouse ES cells using nicotinamide, but not <sc><font size = "-2">L</font></sc>-lysine. … Although immunoreactivity for tyrosine hydroxylase (TH) was almost completely lost in the ipsilateral striatum in hemiparkinsonian rats, TH immunoreactivity was detected in transplanted cells and sprouting fibers. …
NAID 130000074349