An EpCAM/CD3 bispecific antibody efficiently eliminates hepatocellular carcinoma cells with limited galectin-1 expression.
Zhang P, Shi B, Gao H, Jiang H, Kong J, Yan J, Pan X, Li K, Zhang P, Yao M, Yang S, Gu J, Wang H, Li Z.SourceState Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, No. 25/Ln2200, XieTu Rd, Shanghai, 200032, China.
Cancer immunology, immunotherapy : CII.Cancer Immunol Immunother.2013 Nov 1. [Epub ahead of print]
There have been several studies suggesting that cancer stem cells (CSCs) contribute to the high rates of recurrence and resistance to therapies observed in hepatocellular carcinoma (HCC). Epithelial cell adhesion molecule (EpCAM) has been demonstrated to be a biomarker of CSCs and a potential therap
Sensitive Solid-Phase Detection of Donor-Specific Antibodies as an Aid Highly Relevant to Improving Allograft Outcomes.
Schlaf G, Pollok-Kopp B, Altermann WW.SourceTissue Typing Laboratory, University Hospital Halle/Saale, Martin-Luther University of Halle-Wittenberg, Magdeburger Strasse 16, 06112, Halle (Saale), Germany, gerald.schlaf@uk-halle.de.
Molecular diagnosis & therapy.Mol Diagn Ther.2013 Oct 30. [Epub ahead of print]
Transplant recipients who have had sensitizing events such as pregnancies, blood transfusions and previous transplants often develop antibodies directed against human leukocyte antigen (HLA)-molecules of the donor tissue. These pre-formed donor-specific antibodies (DSA) represent a high risk of orga
HLA-universal platelet transfusions prevent platelet refractoriness in a mouse model.
Gras C, Schulze K, Goudeva L, Guzman CA, Blasczyk R, Figueiredo C.SourceHannover Medical School, Institute for Transfusion Medicine, Hannover, Germany ; Gras.Christiane@mh-hannover.de.
Human gene therapy.Hum Gene Ther.2013 Oct 3. [Epub ahead of print]
Refractoriness to platelet (PLT) transfusion caused by alloimmunization against HLA class I antigens constitutes a significant clinical problem. Thus, it would be desirable to have PLT units lacking HLA antigens on the cell surface. Previously, we showed that the generation of functional HLA class I
Transfusion-Related Acute Lung Injury (TRALI) Induced by Donor-Derived Anti-HLA Antibodies in Aplastic Anemia: Possible Priming Effect of Granulocyte-Colony Stimulating Factor (G-CSF) on the Recipient Neutrophils
Antibodies associated with low posttransfusion platelet increments. A comparison between the monoclonal antibody-specific immobilization of platelet antigens assay and the lymphocytotoxicity test
lymphocytotoxicity /lym·pho·cy·to·tox·ic·i·ty/ (-si″to-tok-sis´ĭ-te) the quality or capability of lysing lymphocytes, as in procedures in which lymphocytes having a specific cell surface antigen are lysed when incubated with antisera and ...
lymphocytotoxicity lym·pho·cy·to·tox·ic·i·ty (lim″fo-si″to-tok-sisґĭ-te) the quality or capability of lysing lymphocytes, as that of cytotoxic ... Look at other dictionaries: lymphocytotoxic — lymphocytotoxic, a. Med ...