ルリコナゾール
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/10/17 18:33:22」(JST)
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Luliconazole
|
Systematic (IUPAC) name |
(2E)-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene](1H-imidazol-1-yl)acetonitrile |
Clinical data |
Trade names |
Luzu, Lulicon |
Legal status |
|
Identifiers |
CAS number |
187164-19-8 |
ATC code |
? |
PubChem |
CID 3003141 |
ChemSpider |
2273807 |
Chemical data |
Formula |
C14H9Cl2N3S2 |
Mol. mass |
354.28 g/mol |
SMILES
- C1[C@H](S/C(=C(\C#N)/N2C=CN=C2)/S1)C3=C(C=C(C=C3)Cl)Cl
|
InChI
-
InChI=1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1
Key:YTAOBBFIOAEMLL-REQDGWNSSA-N
|
Luliconazole (Luzu, Lulicon) is an azole antifungal drug. As a 1% topical cream, luliconazole is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by Trichophyton rubrum and Epidermophyton floccosum. [1]
References
- ^ "FDA approves luliconazole for tinea pedis". November 19, 2013. Retrieved 14 January 2014.
External links
- Luliconazole, topicapharma.com
UpToDate Contents
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English Journal
- In vitro activity of new azoles luliconazole and lanoconazole compared with ten other antifungal drugs against clinical dermatophyte isolates.
- Baghi N1, Shokohi T2, Badali H2, Makimura K3, Rezaei-Matehkolaei A4, Abdollahi M5, Didehdar M1, Haghani I2, Abastabar M6.
- Medical mycology.Med Mycol.2016 Apr 26. pii: myw016. [Epub ahead of print]
- In vitro susceptibilities of 100 clinical dermatophyte isolates belonging to five species from Iran toward lanoconazole and luliconazole were compared with ten other antifungal agents including econazole, itraconazole, miconazole, fluconazole, griseofulvin, butenafine, terbinafine, caspofungin, anid
- PMID 27118804
- A critical appraisal of once-daily topical luliconazole for the treatment of superficial fungal infections.
- Gupta AK1, Daigle D2.
- Infection and drug resistance.Infect Drug Resist.2016 Jan 18;9:1-6. doi: 10.2147/IDR.S61998. eCollection 2016.
- Luliconazole is a novel imidazole derivative, which has demonstrated in vitro efficacy against dermatophytes and Candida. The results from Phase III trials show that luliconazole 1% cream applied once daily for 2 weeks successfully resolved the clinical signs and symptoms as well as eradicated the p
- PMID 26848272
- Luliconazole Retention in Stratum Corneum and Prevention of Fungal Infection in a Guinea Pig Tinea Pedis Model.
- Koga H, Nanjoh Y, Toga T, Pillai R, Jo W, Tsuboi R.
- Journal of drugs in dermatology : JDD.J Drugs Dermatol.2016 Jan;15(1):104-8.
- OBJECTIVE: To compare drug concentrations in the stratum corneum following daily application of luliconazole and terbinafine cream in a guinea pig tinea pedis model.METHODS: Luliconazole 1% cream or terbinafine 1% cream were topically applied once daily to hind limbs of guinea pigs for 14 days. Drug
- PMID 26741388
Japanese Journal
- Polyclonality of <I>Trichophyton rubrum</I> Isolates in aDermatophytosis Patient with Multiple Lesions
- ルリコナゾール爪外用液の<I>in vitro</I>爪透過性試験およびスライス阻止円法による爪中薬物濃度分布および抗真菌活性評価
Related Links
- ChemicalBook あなたのためにLuliconazole(187164-19-8)の化学的性質を提供して、融点、価格、蒸気圧、沸点、毒性、比重、沸点、密度、分子式、分子量、物理的な性質、毒性 税関のコードなどの情報、同時にあなたは更に ...
- Luliconazole is a prescription medication used on the skin to treat athlete’s foot that is between the toes, jock itch... ... The common side effect of luliconazole is skin irritation at the site of application. This is not a complete list of ...
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