luliconazole

ルリコナゾール

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/10/17 18:33:22」(JST)

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Luliconazole

Systematic (IUPAC) name
(2E)-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene](1H-imidazol-1-yl)acetonitrile
Clinical data
Trade names	Luzu, Lulicon
Legal status	℞ Prescription only
Identifiers
CAS number	187164-19-8
ATC code	?
PubChem	CID 3003141
ChemSpider	2273807
Chemical data
Formula	C14H9Cl2N3S2
Mol. mass	354.28 g/mol
SMILES C1[C@H](S/C(=C(\C#N)/N2C=CN=C2)/S1)C3=C(C=C(C=C3)Cl)Cl
InChI InChI=1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1 Key:YTAOBBFIOAEMLL-REQDGWNSSA-N

Luliconazole (Luzu, Lulicon) is an azole antifungal drug. As a 1% topical cream, luliconazole is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by Trichophyton rubrum and Epidermophyton floccosum.

References

External links

• Luliconazole, topicapharma.com

UpToDate Contents

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• 1. カンジダ性間擦疹 candidal intertrigo

English Journal

• In vitro activity of new azoles luliconazole and lanoconazole compared with ten other antifungal drugs against clinical dermatophyte isolates.

• Baghi N1, Shokohi T2, Badali H2, Makimura K3, Rezaei-Matehkolaei A4, Abdollahi M5, Didehdar M1, Haghani I2, Abastabar M6.
• Medical mycology.Med Mycol.2016 Apr 26. pii: myw016. [Epub ahead of print]
• In vitro susceptibilities of 100 clinical dermatophyte isolates belonging to five species from Iran toward lanoconazole and luliconazole were compared with ten other antifungal agents including econazole, itraconazole, miconazole, fluconazole, griseofulvin, butenafine, terbinafine, caspofungin, anid
• PMID 27118804

• A critical appraisal of once-daily topical luliconazole for the treatment of superficial fungal infections.

• Gupta AK1, Daigle D2.
• Infection and drug resistance.Infect Drug Resist.2016 Jan 18;9:1-6. doi: 10.2147/IDR.S61998. eCollection 2016.
• Luliconazole is a novel imidazole derivative, which has demonstrated in vitro efficacy against dermatophytes and Candida. The results from Phase III trials show that luliconazole 1% cream applied once daily for 2 weeks successfully resolved the clinical signs and symptoms as well as eradicated the p
• PMID 26848272

• Luliconazole Retention in Stratum Corneum and Prevention of Fungal Infection in a Guinea Pig Tinea Pedis Model.

• Koga H, Nanjoh Y, Toga T, Pillai R, Jo W, Tsuboi R.
• Journal of drugs in dermatology : JDD.J Drugs Dermatol.2016 Jan;15(1):104-8.
• OBJECTIVE: To compare drug concentrations in the stratum corneum following daily application of luliconazole and terbinafine cream in a guinea pig tinea pedis model.METHODS: Luliconazole 1% cream or terbinafine 1% cream were topically applied once daily to hind limbs of guinea pigs for 14 days. Drug
• PMID 26741388

Japanese Journal

• 外用爪白癬治療薬の特性比較

• Medical Mycology Journal 57(4), J141-J147, 2016
• NAID 130005172322

• Polyclonality of <I>Trichophyton rubrum</I> Isolates in aDermatophytosis Patient with Multiple Lesions

• Medical Mycology Journal 57(2), E17-E20, 2016
• NAID 130005155852

• ルリコナゾール爪外用液の<I>in vitro</I>爪透過性試験およびスライス阻止円法による爪中薬物濃度分布および抗真菌活性評価

• Medical Mycology Journal 57(1), J19-J25, 2016
• NAID 130005133121

Related Links

• Luliconazole | 187164-19-8 - ChemicalBook---Chemical ...

ChemicalBook あなたのためにLuliconazole(187164-19-8)の化学的性質を提供して、融点、価格、蒸気圧、沸点、毒性、比重、沸点、密度、分子式、分子量、物理的な性質、毒性 税関のコードなどの情報、同時にあなたは更に ...

• Luliconazole | rxwiki.com - The Leading Drug and Medication ...

Luliconazole is a prescription medication used on the skin to treat athlete’s foot that is between the toes, jock itch... ... The common side effect of luliconazole is skin irritation at the site of application. This is not a complete list of ...

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